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product-image-AAA102679_WB13.jpg WB (Western Blot) (Recombinant protein were subjected to SDS PAGE followed by western blot with AAA102679 (ALK,CD246 Antibody) at dilution of 1:1000)

Mouse ALK, CD246 Monoclonal Antibody | anti-ALK, CD246 antibody

ALK, CD246 Mouse Monoclonal

Gene Names
ALK; CD246; NBLST3
Reactivity
Human; other species are not tested.
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
>=95% as determined by SDS-PAGE
Protein A+G purification
Synonyms
ALK, CD246, Antibody; ALK, CD246 Mouse Monoclonal; ALK, ALK tyrosine kinase receptor, ALK,CD246, Anaplastic lymphoma kinase, CD246, TFG/ALK; anti-ALK, CD246 antibody
Ordering
Host
Mouse
Reactivity
Human; other species are not tested.
Clonality
Monoclonal
Isotype
IgG2a
Specificity
Please decide specifity by homology.
Purity/Purification
>=95% as determined by SDS-PAGE
Protein A+G purification
Form/Format
Liquid
PBS with 0.02% Sodium azide and 50% Glycerol pH 7.3
Sequence Length
1620
Applicable Applications for anti-ALK, CD246 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Immunogen
Anaplastic lymphoma receptor tyrosine kinase
Calculated MW
176 kDa
Preparation and Storage
Store at -20°C for 24 months (Avoid repeated freeze/ thaw cycles)

WB (Western Blot)

(Recombinant protein were subjected to SDS PAGE followed by western blot with AAA102679 (ALK,CD246 Antibody) at dilution of 1:1000)

product-image-AAA102679_WB13.jpg WB (Western Blot) (Recombinant protein were subjected to SDS PAGE followed by western blot with AAA102679 (ALK,CD246 Antibody) at dilution of 1:1000)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human lymphoma slide using AAA102679 (ALK,CD246 Antibody) at dilution of 1:50)

product-image-AAA102679_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human lymphoma slide using AAA102679 (ALK,CD246 Antibody) at dilution of 1:50)
Related Product Information for anti-ALK, CD246 antibody
ALK, also named as CD246, is a receptor tyrosine kinase(RTK) that belongs to the protein kinase superfamily. ALK is usually found in the nervous system and appears to play an important role in the normal development and function of the nervous system. ALK was originally identified as part of the NPM(Nucleophosmin)-ALK oncogenic fusion protein, resulting from the(2;5)(p23;q35)translocation that is frequently associated with anaplastic large-cell lymphoma(ALCL). TheEML4(echinoderm microtubule-associated protein-like 4)-ALK fusion protein have been described in non-small-cell lung cancer(NSCLC), this transforming fusion kinase is a promising candidate for a therapeutic target as well as for a molecular marker in NSCLC(PMID: 17625570).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
238
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
ALK tyrosine kinase receptor
NCBI Official Synonym Full Names
anaplastic lymphoma receptor tyrosine kinase
NCBI Official Symbol
ALK
NCBI Official Synonym Symbols
CD246; NBLST3
NCBI Protein Information
ALK tyrosine kinase receptor
UniProt Protein Name
ALK tyrosine kinase receptor
UniProt Gene Name
ALK
UniProt Entry Name
ALK_HUMAN

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Product Notes

The ALK, CD246 alk (Catalog #AAA102679) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ALK, CD246 Mouse Monoclonal reacts with Human; other species are not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's ALK, CD246 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the ALK, CD246 alk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALK, CD246, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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