WB (Western Blot)
(HepG2 cells were subjected to SDS PAGE followed by western blot with AAA102684 (A2M antibody) at dilution of 1:1000)
Mouse anti-Human Alpha-2-macroglobulin Monoclonal Antibody | anti-A2M antibody
Alpha-2-macroglobulin Mouse Monoclonal
Gene Names
A2M; A2MD; CPAMD5; FWP007; S863-7
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purity: >=95% as determined by SDS-PAGEPurification: Protein A+G purification
Synonyms
Alpha-2-macroglobulin, Antibody; Alpha-2-macroglobulin Mouse Monoclonal; A2M, Alpha 2 M, alpha 2 macroglobulin, CPAMD5, DKFZp779B086, FWP007, S863 7, alpha-2M; anti-A2M antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Specificity
Human; other species are not tested. Please decide the specificity by homology
Purity/Purification
Purity: >=95% as determined by SDS-PAGE
Purification: Protein A+G purification
Purification: Protein A+G purification
Form/Format
Liquid
Sequence Length
1474
Applicable Applications for anti-A2M antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Immunogen
Alpha-2-macroglobulin
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Preparation and Storage
Store -20°C for 24 months (Avoid repeated freeze / thaw cycles.)
WB (Western Blot)
(HepG2 cells were subjected to SDS PAGE followed by western blot with AAA102684 (A2M antibody) at dilution of 1:1000)
WB (Western Blot)
(HepG2 cells were subjected to SDS PAGE followed by western blot with AAA102684 (A2M antibody) at dilution of 1:1000)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human liver slide using AAA102684 (A2M Antibody) at dilution of 1:50)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human liver slide using AAA102684 (A2M Antibody) at dilution of 1:50)
Related Product Information for anti-A2M antibody
Alpha-2-macroglobulin, also known as ?2-macroglobulin (?2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
163kDa, observed 185kDa
NCBI Official Full Name
alpha-2-macroglobulin
NCBI Official Synonym Full Names
alpha-2-macroglobulin
NCBI Official Symbol
A2M
NCBI Official Synonym Symbols
A2MD; CPAMD5; FWP007; S863-7
NCBI Protein Information
alpha-2-macroglobulin
UniProt Protein Name
Alpha-2-macroglobulin
UniProt Gene Name
A2M
UniProt Synonym Gene Names
CPAMD5; Alpha-2-M
UniProt Entry Name
A2MG_HUMAN
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Product Notes
The A2M a2m (Catalog #AAA102684) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Alpha-2-macroglobulin Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Alpha-2-macroglobulin can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the A2M a2m for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Alpha-2-macroglobulin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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