Mouse anti-Human Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody | anti-ACE antibody

Angiotensin I Converting Enzyme (ACE)/CD143 Mouse Monoclonal Antibody [Clone ACE/3764]

Cat. Num. AAA215593

• Gene Names: ACE; DCP; ICH; ACE1; DCP1; CD143; MVCD3
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Synonyms: Angiotensin I Converting Enzyme (ACE)/CD143, Antibody; Angiotensin I Converting Enzyme (ACE)/CD143 Mouse Monoclonal Antibody [Clone ACE/3764]; ACE; ACE1; angiotensin 1 converting enzyme 1; carboxycathepsin; CD143; CD143 antigen; DCP; DCP1; dipeptidyl carboxypeptidase 1; Kininase II; MVCD3; peptidase P; testicular ECA; anti-ACE antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Mouse/IgG1, kappa
• Clone Number: ACE/3764
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Concentration: Purified Ab with BSA and Azide at 200ug/ml; OR; Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)

• Applicable Applications for anti-ACE antibody: IHC (Immunohistochemistry), ELISA
• Immunogen: Full-length recombinant human ACE/CD143 protein
• Cellular Localization: Cell Surface
• Positive Control: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate.
• Hu-chromosome Location: 17q23.3
• Unigene: 298469
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C; Antibody without azide: store at -20 to -80 degree C; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified ACE/CD143 Mouse Monoclonal Antibody (ACE/3764). Confirmation of Integrity and Purity of Antibody.)

Related Product Information for anti-ACE antibody

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

NCBI and Uniprot Product Information

• NCBI GI #: 76057114
• NCBI GeneID: 1636
• UniProt Accession #: P12821; P22966; Q53YX9; Q59GY8; Q7M4L4; B0LPF0; B4DXI3; E7EU16
• Molecular Weight: 149,715 Da
• NCBI Official Full Name: angiotensin I converting enzyme
• NCBI Official Synonym Full Names: angiotensin I converting enzyme
• NCBI Official Symbol: ACE
• NCBI Official Synonym Symbols: DCP; ICH; ACE1; DCP1; CD143; MVCD3
• NCBI Protein Information: angiotensin-converting enzyme; kininase II; peptidase P; CD143 antigen; testicular ECA; carboxycathepsin; dipeptidyl carboxypeptidase 1; dipeptidyl carboxypeptidase I; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptid
• UniProt Protein Name: Angiotensin-converting enzyme
• UniProt Gene Name: ACE
• UniProt Synonym Gene Names: DCP; DCP1; ACE
• UniProt Entry Name: ACE_HUMAN