Mouse anti-Human ANP32A Monoclonal Antibody | anti-ANP32A antibody

ANP32A Monoclonal Antibody

Cat. Num. AAA319943

• Gene Names: ANP32A; LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1
• Reactivity: Human
• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity purification
• Synonyms: ANP32A, Antibody; ANP32A Monoclonal Antibody; Acidic leucine-rich nuclear phosphoprotein 32 family member A; ANP32A; C15orf1; LANP; MAPM; PHAP1; Acidic nuclear phosphoprotein pp32; Leucine-rich acidic nuclear protein; Mapmodulin; Potent heat-stable protein phosphatase 2A inhibito; anti-ANP32A antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Specificity: ANP32A Monoclonal Antibody detects endogenous levels of ANP32A protein.
• Purity/Purification: Affinity purification
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-ANP32A antibody: ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Purified recombinant fragment of human ANP32A expressed in E coli.
• Modification: Unmodified/Total
• Function: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
• PTM: Phosphorylated on serine residues.
• PTM: The N-terminus is blocked.; Belongs to the ANP32 family.; Contains 4 LRR (leucine-rich) repeats.
• Subcellular Location: Shuttles between nucleus and cytoplasm.
• Subunit: Component of the SET complex, which also contains SET, APEX1, HMGB2 and NME1. Directly interacts with SET. Interacts with ATXN1/SCA1. Interacts with MAP1B (By similarity). Interacts with ELAVL1. Part of the INHAT (inhibitor of histone acetyltransferases) complex. Interacts with E4F1.
• Tissue Specificity: Expressed in all tissues tested. Highly expressed in kidney and skeletal muscle, moderate levels of expression in brain, placenta and pancreas, and weakly expressed in lung. Found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala.
• Preparation and Storage: Store at -20 degree C/1 year

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded human kidney tissue with DAB staining using ANP32A Monoclonal Antibody.)

WB (Western Blot)

(Western Blot analysis using ANP32A Monoclonal Antibody against HeLa (1) cell lysate.)

Product Categories/Family for anti-ANP32A antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 5453880
• NCBI GeneID: 8125
• NCBI Accession #: NP_006296.1
• NCBI GenBank Nucleotide #: NM_006305.3
• UniProt Accession #: P39687; Q53FK4; Q5J8L8; Q7M4N6; B2R6T4
• Molecular Weight: 28,585 Da
• NCBI Official Full Name: acidic leucine-rich nuclear phosphoprotein 32 family member A
• NCBI Official Synonym Full Names: acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
• NCBI Official Symbol: ANP32A
• NCBI Official Synonym Symbols: LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1
• NCBI Protein Information: acidic leucine-rich nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein pp32; cerebellar leucine rich acidic nuclear protein; hepatopoietin Cn; inhibitor-1 of protein phosphatase-2A; leucine-rich acidic nuclear protein; mapmodulin; po
• UniProt Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member A
• UniProt Gene Name: ANP32A
• UniProt Synonym Gene Names: C15orf1; LANP; MAPM; PHAP1; pp32; LANP; PHAPI
• UniProt Entry Name: AN32A_HUMAN