ICC (Immunocytochemistry)
(Immunocytochemistry analysis of APC (green) in LNcap using APC antibody,and DAPI(blue).)
Rabbit anti-Human APC Monoclonal Antibody | anti-APC antibody
APC Rabbit mAb
Gene Names
APC; GS; DP2; DP3; BTPS2; DP2.5; PPP1R46
Reactivity
Human
Applications
Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Western Blot
Synonyms
APC, Antibody; APC Rabbit mAb; anti-APC antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
R06-2E4
Form/Format
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Applicable Applications for anti-APC antibody
IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human APC
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
ICC (Immunocytochemistry)
(Immunocytochemistry analysis of APC (green) in LNcap using APC antibody,and DAPI(blue).)
ICC (Immunocytochemistry)
(Immunocytochemistry analysis of APC (green) in LNcap using APC antibody,and DAPI(blue).)
Application Data
Application Data
Related Product Information for anti-APC antibody
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Product Categories/Family for anti-APC antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
311,646 Da
NCBI Official Full Name
adenomatous polyposis coli protein isoform b
NCBI Official Synonym Full Names
adenomatous polyposis coli
NCBI Official Symbol
APC
NCBI Official Synonym Symbols
GS; DP2; DP3; BTPS2; DP2.5; PPP1R46
NCBI Protein Information
adenomatous polyposis coli protein; deleted in polyposis 2.5; adenomatosis polyposis coli tumor suppressor; protein phosphatase 1, regulatory subunit 46
UniProt Protein Name
Adenomatous polyposis coli protein
UniProt Gene Name
APC
UniProt Synonym Gene Names
DP2.5; Protein APC
UniProt Entry Name
APC_HUMAN
Similar Products
Product Notes
The APC apc (Catalog #AAA269520) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC Rabbit mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's APC can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the APC apc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APC, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.