WB (Western Blot)
(HEK-293 cells were subjected to SDS PAGE followed by western blot with AAA102697 (APP Antibody) at dilution of 1:1000)
Mouse anti-Human, Pig APP Monoclonal Antibody | anti-APP antibody
APP Mouse Monoclonal
Gene Names
APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
Reactivity
Human, Pig
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Purification: Protein A+G purification.Purity: > = 95% as determined by SDS-PAGE.
Synonyms
APP, Antibody; APP Mouse Monoclonal; A4, ABPP, Alzheimer disease amyloid protein, cerebral vascular amyloid peptide, Beta-amyloid precursor protein, CV AP, PreA4; anti-APP antibody
Host
Mouse
Reactivity
Human, Pig
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
8B9
Purity/Purification
Purification: Protein A+G purification.
Purity: > = 95% as determined by SDS-PAGE.
Purity: > = 95% as determined by SDS-PAGE.
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Sequence Length
32
Applicable Applications for anti-APP antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Amyloid beta A4 precursor protein.
Preparation and Storage
-20°C for up to 12 months (Avoid repeated freeze/thaw cycles.)
WB (Western Blot)
(HEK-293 cells were subjected to SDS PAGE followed by western blot with AAA102697 (APP Antibody) at dilution of 1:1000)
WB (Western Blot)
(HEK-293 cells were subjected to SDS PAGE followed by western blot with AAA102697 (APP Antibody) at dilution of 1:1000)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human gliomas tissue slide using AAA102697 (APP Antibody) at dilution of 1:200)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human gliomas tissue slide using AAA102697 (APP Antibody) at dilution of 1:200)
Related Product Information for anti-APP antibody
Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalyzed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses. Promotes both tau aggregation and TPK II-mediated phosphorylation. Interaction with overexpressed HADH2 leads to oxidative stress and neurotoxicity. Also binds GPC1 in lipid rafts.
The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Observed MW: 100 kDa
NCBI Official Full Name
amyloid protein, partial
NCBI Official Synonym Full Names
amyloid beta precursor protein
NCBI Official Symbol
APP
NCBI Official Synonym Symbols
AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
NCBI Protein Information
amyloid beta A4 protein
UniProt Protein Name
Amyloid beta A4 protein
UniProt Gene Name
APP
UniProt Synonym Gene Names
A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)
UniProt Entry Name
A4_HUMAN
Similar Products
Product Notes
The APP app (Catalog #AAA102697) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The APP Mouse Monoclonal reacts with Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's APP can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the APP app for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.