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product-image-AAA173469_IP13.jpg IP (Immunoprecipitation) (ASGR1 was immunoprecipitated using:Lane A: 0.5 mg HepG2 Whole Cell Lysate, 2 uL ASGR1 monoclonal antibody and 15 ul of 50 % Protein G agarose.Primary antibody: ASGR1 monoclonal antibody, at dilution of 1:100.)

Rabbit anti-Human ASGR1 Monoclonal Antibody | anti-ASGR1  antibody

Rabbit anti Human ASGR1 Monoclonal Antibody

Gene Names
ASGR1; HL-1; ASGPR; ASGPR1; CLEC4H1
Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Purity
Affinity purification
Synonyms
ASGR1, Antibody; Rabbit anti Human ASGR1 Monoclonal Antibody; 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1; anti-ASGR1  antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
0.2 um filtered solution in PBS with 5% trehalose
Sequence Length
252
Applicable Applications for anti-ASGR1  antibody
IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Recombinant Human ASGPR1 protein
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

IP (Immunoprecipitation)

(ASGR1 was immunoprecipitated using:Lane A: 0.5 mg HepG2 Whole Cell Lysate, 2 uL ASGR1 monoclonal antibody and 15 ul of 50 % Protein G agarose.Primary antibody: ASGR1 monoclonal antibody, at dilution of 1:100.)

product-image-AAA173469_IP13.jpg IP (Immunoprecipitation) (ASGR1 was immunoprecipitated using:Lane A: 0.5 mg HepG2 Whole Cell Lysate, 2 uL ASGR1 monoclonal antibody and 15 ul of 50 % Protein G agarose.Primary antibody: ASGR1 monoclonal antibody, at dilution of 1:100.)

WB (Western Blot)

(Western blot analysis of HepG2 cells using ASGR1 Monoclonal Antibody at dilution of 1:500.)

product-image-AAA173469_WB15.jpg WB (Western Blot) (Western blot analysis of HepG2 cells using ASGR1 Monoclonal Antibody at dilution of 1:500.)
Related Product Information for anti-ASGR1  antibody
The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR belongs to the long-form subfamily of the C-type/Ca2+ dependent lectin family. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1 (MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR1 is synthesized as a type II transmembrane protein that contains a cytosolic N-terminal domain, a single transmembrane segment, and an extracellular domain which contains two important structural regions. The first is a stalk domain that contributes to noncovalent oligomerization, and the second is a Ca2+-dependent carbohydrate binding domain at the very C-terminus that is unusually stabilized by three ions. The research regarded that ASGPR1 could be targeted for anti- hepatitis B virus (HBV) drug development.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
432
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: 32kDa
Observed MW: 48kDa
NCBI Official Full Name
asialoglycoprotein receptor 1 isoform b
NCBI Official Synonym Full Names
asialoglycoprotein receptor 1
NCBI Official Symbol
ASGR1
NCBI Official Synonym Symbols
HL-1; ASGPR; ASGPR1; CLEC4H1
NCBI Protein Information
asialoglycoprotein receptor 1
UniProt Protein Name
Asialoglycoprotein receptor 1
UniProt Gene Name
ASGR1
UniProt Synonym Gene Names
CLEC4H1; ASGP-R 1; ASGPR 1; HL-1
UniProt Entry Name
ASGR1_HUMAN

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Product Notes

The ASGR1  asgr1 (Catalog #AAA173469) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human ASGR1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ASGR1 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the ASGR1  asgr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASGR1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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