IHC (Immunohiostchemistry)
(IHC of BAP1 on an FFPE Normal Breast tissue)
Rabbit anti-Human BAP1 Monoclonal Antibody | anti-BAP1 antibody
BAP1 (RBT-BAP1), RMab
Reactivity
Human
Synonyms
BAP1, Antibody; BAP1 (RBT-BAP1), RMab; BAP1, (RBT-BAP1); TFF3; trefoil factor 3 intestinal; ITF; P1B; TFI; anti-tff3; anti-itf; anti-BAP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
RBT-BAP1
Form/Format
This antibody is derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide.
Localization
Nuclear
Intended Use
BAP1 (RBT-BAP1), rabbit monoclonal antibody, is a primary antibody intended for laboratory use by trained laboratory personnel in an immunohistochemical (IHC) assay to qualitatively identify the BAP1 protein by light microscopy in normal and/or pathological formalin-fixed, paraffin-embedded (FFPE) human tissue.
The clinical interpretation of any staining or its absence should be performed by a qualified pathologist and complemented by morphological studies using proper controls and evaluated within the context of the patient’s clinical history and other tests.
The clinical interpretation of any staining or its absence should be performed by a qualified pathologist and complemented by morphological studies using proper controls and evaluated within the context of the patient’s clinical history and other tests.
IHC (Immunohiostchemistry)
(IHC of BAP1 on an FFPE Normal Breast tissue)
IHC (Immunohiostchemistry)
(IHC of BAP1 on an FFPE Normal Breast tissue)
Dilution Info
Dilution Info
Related Product Information for anti-BAP1 antibody
BAP1 or BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) is a deubiquitinating enzyme that in humans is encoded by the BAP1 gene. In cancer, BAP1 can function both as a tumor suppressor and as a metastasis suppressor. Exome sequencing identified inactivating mutations in BAP1 in 47% of Uveal melanomas, and BAP1 mutation have been found to be strongly associated with metastasis. BAP1 mutations have been identified in aggressive Mesotheliomas with similar mutations as seen in Melanomas. Mutations in the tumor suppressor gene BAP1 occur in approximately 15% of clear cell renal cell carcinoma cases. Sequencing efforts demonstrated worse outcomes in patients with BAP1 mutated clear cell renal cell carcinoma.
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Product Notes
The BAP1 (Catalog #AAA59491) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BAP1 (RBT-BAP1), RMab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "BAP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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