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FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells using Bcl-10 Monoclonal Antibody (green) and negative control (purple).)
Mouse anti-Human, Mouse Bcl-10 Monoclonal Antibody | anti-Bcl-10 antibody
Bcl-10 Monoclonal Antibody
Gene Names
BCL10; CLAP; mE10; CIPER; c-E10; CARMEN
Reactivity
Human, Mouse
Applications
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
Bcl-10, Antibody; Bcl-10 Monoclonal Antibody; B-cell lymphoma/leukemia 10; BCL10; CIPER; CLAP; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; Cellular homolog; anti-Bcl-10 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Specificity
Bcl-10 Monoclonal Antibody detects endogenous levels of Bcl-10 protein.
Purity/Purification
Affinity purification
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-Bcl-10 antibody
ELISA, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of human Bcl-10 expressed in E coli.
Modification
Unmodified/Total
Preparation and Storage
Store at -20 degree C/1 year
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells using Bcl-10 Monoclonal Antibody (green) and negative control (purple).)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells using Bcl-10 Monoclonal Antibody (green) and negative control (purple).)
IF (Immunofluorescence)
(Confocal immunofluorescence analysis of Hela cells using Bcl-10 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.)
IF (Immunofluorescence)
(Confocal immunofluorescence analysis of Hela cells using Bcl-10 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma (A) and liver carcinoma (B). showing cytoplasmic localization with DAB staining using Bcl-10 Monoclonal Antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma (A) and liver carcinoma (B). showing cytoplasmic localization with DAB staining using Bcl-10 Monoclonal Antibody.)
WB (Western Blot)
(Western Blot analysis using Bcl-10 Monoclonal Antibody against NIH/3T3 (1). HeLa (2). MCF-7 (3) and Jurkat (4) cell lysate.)
WB (Western Blot)
(Western Blot analysis using Bcl-10 Monoclonal Antibody against NIH/3T3 (1). HeLa (2). MCF-7 (3) and Jurkat (4) cell lysate.)
Related Product Information for anti-Bcl-10 antibody
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma.The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Product Categories/Family for anti-Bcl-10 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,252 Da
NCBI Official Full Name
B-cell lymphoma/leukemia 10
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 10
NCBI Official Symbol
BCL10
NCBI Official Synonym Symbols
CLAP; mE10; CIPER; c-E10; CARMEN
NCBI Protein Information
B-cell lymphoma/leukemia 10; hCLAP; cCARMEN; cellular-E10; cellular homolog of vCARMEN; CARD-containing proapoptotic protein; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; caspase-recruiting domain-containing prote
UniProt Protein Name
B-cell lymphoma/leukemia 10
UniProt Gene Name
BCL10
UniProt Synonym Gene Names
CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10
UniProt Entry Name
BCL10_HUMAN
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Product Notes
The Bcl-10 bcl10 (Catalog #AAA319961) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Bcl-10 Monoclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Bcl-10 can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Bcl-10 bcl10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bcl-10, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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