SDS-PAGE
(SDS-PAGE Analysis Purified B2M Rabbit Recombinant Monoclonal Antibody (B2M/7013R). Confirmation of Purity and Integrity of Antibody)
Rabbit Beta-2 Microglobulin Monoclonal Antibody | anti-B2M antibody
Beta-2 Microglobulin (Renal Failure & Tumor Marker) Recombinant Rabbit Monoclonal Antibody [Clone B2M/7013R]
Reactivity
Human and non-human primates.
Applications
Immunohistochemistry
Synonyms
Beta-2 Microglobulin, Antibody; Beta-2 Microglobulin (Renal Failure & Tumor Marker) Recombinant Rabbit Monoclonal Antibody [Clone B2M/7013R]; Beta-2 Microglobulin (Renal Failure & Tumor Marker); B2M; Beta 2 microglobin; Beta 2 microglobulin; Beta chain of MHC class I molecules; Beta-2-microglobulin form pI 5. 3; Hdcma22p; anti-B2M antibody
Host
Rabbit
Reactivity
Human and non-human primates.
Clonality
Monoclonal
Isotype
Rabbit/IgG
Clone Number
B2M/7013R
Form/Format
200ug/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-B2M antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant full-length human B2M protein
Cellular Localization
Cell Surface, Extracellular (Secreted)
Positive Control
Raji, HL-60 or HeLa cells. Human carcinomas of stomach, cervix, endometrial, kidney or colon.
Hu-chromosome Location
15q21-q22.2
Unigene
534255
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified B2M Rabbit Recombinant Monoclonal Antibody (B2M/7013R). Confirmation of Purity and Integrity of Antibody)
SDS-PAGE
(SDS-PAGE Analysis Purified B2M Rabbit Recombinant Monoclonal Antibody (B2M/7013R). Confirmation of Purity and Integrity of Antibody)
Related Product Information for anti-B2M antibody
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
119
NCBI Official Full Name
Beta-2-microglobulin
NCBI Official Synonym Full Names
beta-2-microglobulin
NCBI Official Symbol
B2M
NCBI Protein Information
beta-2-microglobulin; beta-2-microglobin; beta chain of MHC class I molecules
UniProt Protein Name
Beta-2-microglobulin
UniProt Gene Name
B2M
UniProt Entry Name
B2MG_HUMAN
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Product Notes
The B2M b2m (Catalog #AAA215863) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Beta-2 Microglobulin (Renal Failure & Tumor Marker) Recombinant Rabbit Monoclonal Antibody [Clone B2M/7013R] reacts with Human and non-human primates. and may cross-react with other species as described in the data sheet. AAA Biotech's Beta-2 Microglobulin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the B2M b2m for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beta-2 Microglobulin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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