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product-image-AAA215987_SDS_PAGE15.jpg SDS-PAGE (SDS-PAGE Analysis Purified CA8 Mouse Monoclonal Antibody (CA8/6572). Confirmation of Purity and Integrity of Antibody.)

Mouse anti-Human Carbonic Anhydrase VIII Monoclonal Antibody | anti-CA8 antibody

Carbonic Anhydrase VIII Mouse Monoclonal Antibody [Clone CA8/6572]

Gene Names
CA8; CALS; CARP; CAMRQ3; CA-VIII
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Carbonic Anhydrase VIII, Antibody; Carbonic Anhydrase VIII Mouse Monoclonal Antibody [Clone CA8/6572]; CA-VIII; CALS; CARP; MGC120502; MGC99509; anti-CA8 antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2a, kappa
Clone Number
CA8/6572
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-CA8 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant full-length human CA8 protein
Cellular Localization
Cytoplasm, Cell surface
Positive Control
Human cerebellum. Selective expression in Purkinje cells. HEK-293 or K-562 cell lines.
Hu-chromosome Location
8q12.1
Unigene
654388
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified CA8 Mouse Monoclonal Antibody (CA8/6572). Confirmation of Purity and Integrity of Antibody.)

product-image-AAA215987_SDS_PAGE15.jpg SDS-PAGE (SDS-PAGE Analysis Purified CA8 Mouse Monoclonal Antibody (CA8/6572). Confirmation of Purity and Integrity of Antibody.)
Related Product Information for anti-CA8 antibody
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i. e. , the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
767
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,973 Da
NCBI Official Full Name
carbonic anhydrase-related protein
NCBI Official Synonym Full Names
carbonic anhydrase VIII
NCBI Official Symbol
CA8
NCBI Official Synonym Symbols
CALS; CARP; CAMRQ3; CA-VIII
NCBI Protein Information
carbonic anhydrase-related protein; CA-related protein; carbonate dehydratase; carbonic anhydrase-like sequence
UniProt Protein Name
Carbonic anhydrase-related protein
UniProt Gene Name
CA8
UniProt Synonym Gene Names
CALS; CARP; CA-VIII
UniProt Entry Name
CAH8_HUMAN

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Product Notes

The CA8 ca8 (Catalog #AAA215987) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Carbonic Anhydrase VIII Mouse Monoclonal Antibody [Clone CA8/6572] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Carbonic Anhydrase VIII can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CA8 ca8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Carbonic Anhydrase VIII, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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