Application Data
(Figure A. FITC conjugated mouse anti human CD19 and Alexa647 conjugated Mouse IgG1 isotype control . Figure B. FITC conjugated mouse anti human CD19 and Alexa647 conjugated mouse anti human CD10 . All experiments performed on red cell lysed Human peripheral blood gated on leukocytes in the presence of Human SeroBlock .)
Mouse anti-Human CD10 Monoclonal Antibody | anti-CD10 antibody
Mouse Anti Human CD10: Amethyst Orange
Gene Names
MME; NEP; SFE; CD10; CALLA; CMT2T; SCA43
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Synonyms
CD10, Antibody; Mouse Anti Human CD10: Amethyst Orange; CD10 antibody, SN5c; anti-CD10 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
SN5c
Purity/Purification
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Form/Format
Purified IgG conjugated to Amethyst Orange - Liquid
Concentration
IgG concentration 0.1 mg/ml (varies by lot)
Sequence Length
750
Applicable Applications for anti-CD10 antibody
FCM/FACS (Flow Cytometry)
Immunogen
Partially purified cell membrane antigens from fresh leukemia cells
Buffer Solution
Phosphate Buffered Saline
Preservative Stabilizers
0.09% Sodium Azide (NaN3) 1% Bovine Serum Albumin
Fusion Partners
Spleen cells from immunized BALB/c mice were fused with cells of the mouse PS/NS1/1-Ag4-1 myeloma cell line.
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody.
This product contains a precipitate we recommend microcentrifugation before use.
This product should be stored undiluted.
Storage in frost free freezers is not recommended.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody.
This product contains a precipitate we recommend microcentrifugation before use.
Application Data
(Figure A. FITC conjugated mouse anti human CD19 and Alexa647 conjugated Mouse IgG1 isotype control . Figure B. FITC conjugated mouse anti human CD19 and Alexa647 conjugated mouse anti human CD10 . All experiments performed on red cell lysed Human peripheral blood gated on leukocytes in the presence of Human SeroBlock .)
Application Data
(Figure A. FITC conjugated mouse anti human CD19 and Alexa647 conjugated Mouse IgG1 isotype control . Figure B. FITC conjugated mouse anti human CD19 and Alexa647 conjugated mouse anti human CD10 . All experiments performed on red cell lysed Human peripheral blood gated on leukocytes in the presence of Human SeroBlock .)
Application Data
(FITC conjugated Mouse anti Human CD11b and Amethyst Orange conjugated Mouse IgG1 isotype control . Figure B. FITC conjugated Mouse anti Human CD3 and Amethyst Orange conjugated Mouse anti Human CD10 . All experiments performed on human blood gated on live single granulocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer)
Application Data
(FITC conjugated Mouse anti Human CD11b and Amethyst Orange conjugated Mouse IgG1 isotype control . Figure B. FITC conjugated Mouse anti Human CD3 and Amethyst Orange conjugated Mouse anti Human CD10 . All experiments performed on human blood gated on live single granulocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer)
Related Product Information for anti-CD10 antibody
Mouse anti Human CD10 antibody, clone SN5c recognizes human neprilysin, also known as CD10, atriopeptidase, enkephalinase, neutral endopeptiddase 24.11, skin fibroblast elastase or common acute lymphocytic leukemia antigen (CALLA). CD10 is a 749 aminoacid, ~100 kDa single pass type II transmembrane glycoprotein expressed by acute lymphoblastic leukaemia cells and by peripheral blood granulocytes.
Defects in the MME gene encoding CD10 can lead to the development of the peripheral nervous system disorder, Charcot-Marie-Tooth disease 2T (CMY2T), an axonal form of Marie-Charcot-Tooth disease characterized by either doninantly inherited primary peripheral demyelinating neuropathies, designated CMT1, or primary peripheral axonal neuropathies showing axonal degeneration in the absence of any obvious myelin alteration (CMT2).
Defects in the MME gene encoding CD10 can lead to the development of the peripheral nervous system disorder, Charcot-Marie-Tooth disease 2T (CMY2T), an axonal form of Marie-Charcot-Tooth disease characterized by either doninantly inherited primary peripheral demyelinating neuropathies, designated CMT1, or primary peripheral axonal neuropathies showing axonal degeneration in the absence of any obvious myelin alteration (CMT2).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
neprilysin isoform a
NCBI Official Synonym Full Names
membrane metalloendopeptidase
NCBI Official Symbol
MME
NCBI Official Synonym Symbols
NEP; SFE; CD10; CALLA; CMT2T; SCA43
NCBI Protein Information
neprilysin
UniProt Protein Name
Neprilysin
UniProt Gene Name
MME
UniProt Synonym Gene Names
EPN; CALLA; NEP; Neutral endopeptidase; SFE
UniProt Entry Name
NEP_HUMAN
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Product Notes
The CD10 mme (Catalog #AAA50396) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human CD10: Amethyst Orange reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD10 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD10 mme for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD10, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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