Mouse CD140b Monoclonal Antibody | anti-CD140b antibody
MOUSE ANTI HUMAN CD140b
Gene Names
PDGFRB; IMF1; IBGC4; JTK12; PDGFR; CD140B; PDGFR1; PDGFR-1
Applications
Western Blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescence, Flow Cytometry, Functional Assay, Immunohistochemistry
Purity
Purified IgG prepared by affinity chromatography on Protein G from ascites
Synonyms
CD140b, Antibody; MOUSE ANTI HUMAN CD140b; anti-CD140b antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
PR7212
Specificity
Mouse anti Human CD140b antibody, clone PR7212 recognizes the extracellular domain of the human PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB (Hart et al. 1987). Mouse anti Human CD140b antibody, clone PR7212 does not recognize PDGF receptor alpha.
PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
Purity/Purification
Purified IgG prepared by affinity chromatography on Protein G from ascites
Form/Format
Liquid
Concentration
Approximate Protein Concentration: 1.0 mg/ml (varies by lot)
Sequence Length
1106
Applicable Applications for anti-CD140b antibody
WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
Perservative Stabilisers
<0.1% Sodium Azide (NaN3)
Species Cross Reactivity
Baboon, Monkey
Does not react with mouse or rat.
N.B. Antibody reactivity and working conditions may vary between species.
Does not react with mouse or rat.
N.B. Antibody reactivity and working conditions may vary between species.
Immunogen
Human skin fibroblast cell membrane extracts
Histology Positive Control Tissue
Human breast cancer tissue
Buffer Solution
Phosphate buffered saline
Target Species
Human
Preparation and Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt.
When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Shelf Life: 12 months from date of despatch.
When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Shelf Life: 12 months from date of despatch.
Related Product Information for anti-CD140b antibody
MBS211868 is specific for the extracellular domain of the human PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. MBS211868 does not recognize PDGF receptor alpha.PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
platelet-derived growth factor receptor beta
NCBI Official Synonym Full Names
platelet-derived growth factor receptor, beta polypeptide
NCBI Official Symbol
PDGFRB
NCBI Official Synonym Symbols
IMF1; IBGC4; JTK12; PDGFR; CD140B; PDGFR1; PDGFR-1
NCBI Protein Information
platelet-derived growth factor receptor beta; CD140 antigen-like family member B; PDGF-R-beta; PDGFR-beta; beta-type platelet-derived growth factor receptor; platelet-derived growth factor receptor 1
UniProt Protein Name
Platelet-derived growth factor receptor beta
UniProt Gene Name
PDGFRB
UniProt Synonym Gene Names
PDGFR; PDGFR1; PDGF-R-beta; PDGFR-beta; PDGFR-1
UniProt Entry Name
PGFRB_HUMAN
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Product Notes
The CD140b pdgfrb (Catalog #AAA49203) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD140b can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD140b pdgfrb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD140b, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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