Mouse anti-Rat CD161 Monoclonal Antibody | anti-CD161 antibody
Anti-Rt CD161 Purified
Gene Names
Klrb1; Klrb6; Klrb1d; Klrb1f; Klrb1g; NKR-P1G; Nkr-p1e; Nkrp-1e
Reactivity
Rat
Applications
immunoassay, Radioimmunoassay, Immunohistochemistry, Western Blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
CD161, Antibody; Anti-Rt CD161 Purified; killer cell lectin-like receptor subfamily B, memb; NKRP1A; Klrb; anti-CD161 antibody
Host
Mouse
Reactivity
Rat
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
10/78
Specificity
The mouse monoclonal antibody 10/78 recognizes CD161, an approximately 30 kDa type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer. A common extracellular epitope on rat CD161a and b isoforms is detected.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
214
Applicable Applications for anti-CD161 antibody
RIA (Radioimmunoassay), IHC (Immunohistochemistry), WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry)
Immunogen
Splenic cells purified from the LEW rat
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-CD161 antibody
CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
killer cell lectin-like receptor subfamily B member 1
NCBI Official Synonym Full Names
killer cell lectin like receptor B1
NCBI Official Symbol
Klrb1
NCBI Official Synonym Symbols
Klrb6; Klrb1d; Klrb1f; Klrb1g; NKR-P1G; Nkr-p1e; Nkrp-1e
NCBI Protein Information
killer cell lectin-like receptor subfamily B member 1
UniProt Protein Name
Killer cell lectin-like receptor subfamily B member 1
UniProt Gene Name
Klrb1
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Product Notes
The CD161 klrb1 (Catalog #AAA128252) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Rt CD161 Purified reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD161 can be used in a range of immunoassay formats including, but not limited to, RIA (Radioimmunoassay), IHC (Immunohistochemistry), WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD161 klrb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD161, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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