Rat CD206 Monoclonal Antibody | anti-CD206 antibody
RAT ANTI MOUSE CD206
Gene Names
Mrc1; MR; CD206; AW259686
Applications
Immunoprecipitation, Immunofluorescence, Flow Cytometry, Functional Assay, Immunohistochemistry
Synonyms
CD206, Antibody; RAT ANTI MOUSE CD206; MANNOSE RECEPTOR C TYPE 1; anti-CD206 antibody
Host
Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
MR5D3
Specificity
Rat anti mouse CD206 antibody, clone MR5D3 recognizes the mouse mannose receptor, a ~175 kDa type 1 membrane glycoprotein that is also known as CD206. CD206 is expressed on most tissue macrophages, certain endothelial cells and in vitro derived dendritic cells. The mannose receptor, CD206, is composed of a N-terminal cysteine-rich domain, a fibronectin type II domain, eight tandemly arranged C-type lectin domains (CTLD), a transmembrane domain, and a cytoplasmic domain. The terminal cysteine-rich domain binds sulfated sugars, and the CTLD recognizes carbohydrates terminating in mannose, fucose and N-acetylglucosamine, all sugars found on microorganisms and on some endogenous proteins. Rat anti mouse CD206 antibody, clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands. Clone MR5D3 has also been shown to work in western blotting.
Form/Format
Liquid; purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
1456
Applicable Applications for anti-CD206 antibody
IP (Immunoprecipitation), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
Perservative Stabilizers
0.09% Sodium Azide (NaN3)
Carrier Free
Yes
Immunogen
Chimaeric CRD4-7-Fc protein
Buffer Solution
Phosphate buffered saline
Target Species
Mouse
RRID
AB_1101333
Fusion Partner
Spleen cells from immunized Fischer rats were fused with cells of the Y3 myeloma cell line.
Preparation and Storage
It is recommended to aliquot and store at -20 degree C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8 degree C for short term use (up to 4 weeks) and store the remaining aliquots at -20 degree C. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
macrophage mannose receptor 1
NCBI Official Synonym Full Names
mannose receptor, C type 1
NCBI Official Symbol
Mrc1
NCBI Official Synonym Symbols
MR; CD206; AW259686
NCBI Protein Information
macrophage mannose receptor 1; MMR
UniProt Protein Name
Macrophage mannose receptor 1
UniProt Gene Name
Mrc1
UniProt Synonym Gene Names
MMR
UniProt Entry Name
MRC1_MOUSE
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Product Notes
The CD206 mrc1 (Catalog #AAA49652) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD206 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD206 mrc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD206, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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