Mouse CD38 Monoclonal Antibody | anti-CD38 antibody

CD38

Cat. Num. AAA59253

• Gene Names: CD38; T10
• Reactivity: Human, Rabbit
• Synonyms: CD38, Antibody; CD38; anti-CD38 antibody

• Host: Mouse
• Reactivity: Human, Rabbit
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: SPC32
• Form/Format: Anti-CD38 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5,containing BSA and sodium azide as a preservative.

• Control: Tonsil, Lymph Node
• Localization: Membranous
• Immunogen: Recombinant protein encoding the extracellular domain of human CD38.
• Reactivity Note: Paraffin, Frozen
• Precautions: 1. This product contains <0.1% sodium azide (NaN3) as a preservative. Ensure proper handling procedures are used with this reagent.; 2. Always wear personal protective equipment such as a laboratorycoat, goggles, and gloves when handling reagents.; 3. Dispose of unused solution with copious amounts of water.; 4. Do not ingest reagent. If reagent is ingested,seek medical advice immediately.; 5. Avoid contact with eyes. If contact occurs, flush with large quantities of water.; 6. Follow safety precautions of the heating device used for epitope retrieval (TintoRetriever Pressure Cooker or similar).; 7. For additional safetyinformation refer to Safety Data Sheet for this product.; 8. For complete recommendations for handling biological specimens, please refer to the CDC document,“Guidelines for Safe Work Practices in Human and AMDL”
• Specimen Preparation: Paraffin sections:; The antibodycan be used on formalin-fixed paraffin-embedded (FFPE) tissue sections. Ensure tissue undergoes appropriate fixation for best results. Pre-treatment of tissues with heat-induced epitope retrieval (HIER) is recommended using ImmunoDNA Retriever with Citrate, ImmunoDNA Retriever with EDTA, or ImmunoDNA Digestor. See reverse side for complete protocol. Tissue should remain hydrated via use of Bio SB Immuno/DNAWasher solutions.
• Mounting Protocols: For detailed instructions using biodegradable permanent mounting media such as XyGreen PermaMounter (BSB 0169-0174) or organic solvent based resin such as PermaMounter.
• Product Limitations: Due to inherent variability present in immunohistochemical procedures (including fixation time of tissues, dilution factor of antibody, retrieval method utilized, and incubation time), optimal performance should be established through the use of positive and negative controls.
• Preparation and Storage: Store at 2-8°C

IHC (Immunohistochemistry)

IHC (Immunohiostchemistry)

Dilution Info

Related Product Information for anti-CD38 antibody

CD38 is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It is a marker of cell activation. The CD38 protein has been connected to HIV infection, Leukemias, Myelomas, solid tumors, Type II Diabetes Mellitus and bone metabolism, as well as some genetically-determined conditions. It has also been used as a prognostic marker in Leukemia. CD38 is highly expressed on thymocytes. It is also expressed by early cells of B and T lineages, NK cells, plasma cells, monocytes and macrophages, and may be detected on cells from Multiple Myeloma, ALL (B and T) and some AML. Monoclonal antibodies to CD38 have been shown to be useful in subtyping of Lymphomas and Leukemias, inhibition of B-lymphopoiesis, detection of plasma cells, protection of B-cells from apoptosis, and as a marker for activated B and T-cell proliferation.

NCBI and Uniprot Product Information

• NCBI GI #: 1911103
• NCBI GeneID: 952
• UniProt Accession #: P28907; O00121; O00122; Q96HY4; Q4FCX6
• NCBI Official Full Name: CD38
• NCBI Official Synonym Full Names: CD38 molecule
• NCBI Official Symbol: CD38
• NCBI Official Synonym Symbols: T10
• NCBI Protein Information: ADP-ribosyl cyclase 1; cADPr hydrolase 1; CD38 antigen (p45); OTTHUMP00000158633; OTTHUMP00000217743; NAD(+) nucleosidase; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
• UniProt Protein Name: ADP-ribosyl cyclase 1
• UniProt Gene Name: CD38
• UniProt Entry Name: CD38_HUMAN