Rabbit CD3e Monoclonal Antibody | anti-CD3E antibody

CD3e (T-Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone C3e/4652R]

Cat. Num. AAA216031

• Gene Names: CD3E; T3E; TCRE; IMD18
• Reactivity: Human; Does not react with Cat or Dog.
• Applications: Immunohistochemistry, Western Blot, ELISA
• Synonyms: CD3e, Antibody; CD3e (T-Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone C3e/4652R]; CD3e (T-Cell Marker); CD3 epsilon; CD3 TCR complex; T cell antigen receptor complex epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE; TiT3 complex; anti-CD3E antibody

• Host: Rabbit
• Reactivity: Human; Does not react with Cat or Dog.
• Clonality: Monoclonal
• Isotype: Rabbit/IgG
• Clone Number: C3e/4652R
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Concentration: Purified Ab with BSA and Azide at 200ug/ml; OR; Purified Ab WITHOUT BSA at 1.0mg/ml (varies by lot)

• Applicable Applications for anti-CD3E antibody: IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Antibody Type: Recombinant Antibody
• Immunogen: A synthetic peptide from human CD3e protein (around aa 20-40) (exact sequence is proprietary)
• Cellular Localization: Cell surface, Cytoplasm
• Positive Control: Human peripheral blood. Jurkat cells. Tonsil or lymph node.
• Hu-chromosome Location: 11q23.3
• Unigene: 3003
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C; Antibody without azide: store at -20 to -80 degree C; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human lymph node stained with CD3e Recombinant Rabbit Monoclonal Antibody (C3e/4652R).)

Related Product Information for anti-CD3E antibody

Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

NCBI and Uniprot Product Information

• NCBI GI #: 1345708
• NCBI GeneID: 916
• UniProt Accession #: P07766; A8K997
• Molecular Weight: 207
• NCBI Official Full Name: T-cell surface glycoprotein CD3 epsilon chain
• NCBI Official Synonym Full Names: CD3e molecule, epsilon (CD3-TCR complex)
• NCBI Official Symbol: CD3E
• NCBI Official Synonym Symbols: T3E; TCRE; IMD18
• NCBI Protein Information: T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
• UniProt Protein Name: T-cell surface glycoprotein CD3 epsilon chain
• UniProt Gene Name: CD3E
• UniProt Synonym Gene Names: T3E
• UniProt Entry Name: CD3E_HUMAN