IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with CD40 Recombinant Rabbit Monoclonal Antibody (C40/4826R).)
Rabbit anti-Human CD40/TNFRSF5/CD40L-Receptor Monoclonal Antibody | anti-CD40 antibody
CD40/TNFRSF5/CD40L-Receptor Recombinant Rabbit Monoclonal Antibody [Clone C40/4826R]
Gene Names
CD40; p50; Bp50; CDW40; TNFRSF5
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Synonyms
CD40/TNFRSF5/CD40L-Receptor, Antibody; CD40/TNFRSF5/CD40L-Receptor Recombinant Rabbit Monoclonal Antibody [Clone C40/4826R]; B-cell surface antigen CD40; Bp50; CD40; CD40L receptor; GP39; HIGM1; IGM; IMD3; p50; TBAM; TNF receptor superfamily member 5; TNFRSF5; TRAP; anti-CD40 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG
Clone Number
C40/4826R
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-CD40 antibody
IHC (Immunohistochemistry), ELISA
Antibody Type
Recombinant Antibody
Immunogen
Recombinant fragment of human CD40 protein (around aa 29-107) (exact sequence is proprietary)
Cellular Localization
Cell Surface, Secreted
Positive Control
U2OS or L-428 cells. Human tonsil, spleen or thymus.
Hu-chromosome Location
20q12-q13.2
Unigene
472860
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with CD40 Recombinant Rabbit Monoclonal Antibody (C40/4826R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with CD40 Recombinant Rabbit Monoclonal Antibody (C40/4826R).)
Related Product Information for anti-CD40 antibody
CD40 is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is expressed on B-lymphocytes, follicular dendritic cells, bone marrow-derived dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zones of secondary lymphoid organs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,619 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 5 isoform 1
NCBI Official Synonym Full Names
CD40 molecule, TNF receptor superfamily member 5
NCBI Official Symbol
CD40
NCBI Official Synonym Symbols
p50; Bp50; CDW40; TNFRSF5
NCBI Protein Information
tumor necrosis factor receptor superfamily member 5; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; B-cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor recept
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 5
UniProt Gene Name
CD40
UniProt Synonym Gene Names
TNFRSF5
UniProt Entry Name
TNR5_HUMAN
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Product Notes
The CD40 cd40 (Catalog #AAA216068) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD40/TNFRSF5/CD40L-Receptor Recombinant Rabbit Monoclonal Antibody [Clone C40/4826R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD40/TNFRSF5/CD40L-Receptor can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the CD40 cd40 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD40/TNFRSF5/CD40L-Receptor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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