WB (Western Blot)
(Western blot detection of CD41 in C6, Hela cell lysates using CD41 antibody(1:1000 diluted).)
Rabbit anti-Human CD41 Monoclonal Antibody | anti-CD41 antibody
CD41
Gene Names
ITGA2B; GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Protein A affinity purified
Synonyms
CD41, Antibody; CD41; Integrin alpha-IIb; GPalpha IIb; Platelet membrane glycoprotein IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; form 1; form 2; anti-CD41 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
JM11-19
Purity/Purification
Protein A affinity purified
Form/Format
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.20% Sodium Azide
Sequence Length
1039
Applicable Applications for anti-CD41 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein.
Positive control
Human placenta tissue lysates, human tonsil tissue, human spleen tissue.
Subcellular location
Membrane.
Preparation and Storage
Aliquot and store at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
WB (Western Blot)
(Western blot detection of CD41 in C6, Hela cell lysates using CD41 antibody(1:1000 diluted).)
WB (Western Blot)
(Western blot detection of CD41 in C6, Hela cell lysates using CD41 antibody(1:1000 diluted).)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue with Rabbit anti-CD41 antibody at 1/100 dilution.The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA bu fer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue with Rabbit anti-CD41 antibody at 1/100 dilution.The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA bu fer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX)
WB (Western Blot)
(Western blot analysis of CD41 on human placenta tissue lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:200,000 dilution was used for 1 hour at room temperature.)
WB (Western Blot)
(Western blot analysis of CD41 on human placenta tissue lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:200,000 dilution was used for 1 hour at room temperature.)
Related Product Information for anti-CD41 antibody
Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16 ? and 8 ? subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted band size: 113 kDa
NCBI Official Full Name
integrin alpha-IIb preproprotein
NCBI Official Synonym Full Names
integrin subunit alpha 2b
NCBI Official Symbol
ITGA2B
NCBI Official Synonym Symbols
GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93
NCBI Protein Information
integrin alpha-IIb
UniProt Protein Name
Integrin alpha-IIb
UniProt Gene Name
ITGA2B
UniProt Synonym Gene Names
GP2B; ITGAB; GPIIb
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Product Notes
The CD41 itga2b (Catalog #AAA268417) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD41 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD41 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CD41 itga2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD41, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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