IHC (Immunohiostchemistry)
Mouse anti-Human CD44 Monoclonal Antibody | anti-CD44 antibody
CD44
Gene Names
CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; MGC10468
Reactivity
Human
Synonyms
CD44, Antibody; CD44; anti-CD44 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
MRQ-13
Form/Format
CD44 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Tonsil, Kidney, Esophageal CA
Localization
Membranous
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
Dilution Info
Dilution Info
Related Product Information for anti-CD44 antibody
The CD44 protein is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. CD44 is also known as Homing-cell adhesion molecule (H-CAM) and Phagocytic glycoprotein-1 (PgP-1). A specialized sialofucosylated glycoform of CD44 called HCELL is found natively on human hematopoietic stem cells and functions as a "bone-homing receptor", directing migration of human hematopoietic stem cells and mesenchymal stem cells to bone marrow. This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms; however, the full-length nature of some of these variants has not been determined. Splice variants of CD44 on Colon Cancer cells display the HCELL glycoform, which mediates binding to vascular E-selectin under hemodynamic flow conditions, a critical step in Colon Cancer metastasis. In addition, variations in CD44 are reported as cell surface markers for some breast and prostate cancer stem cells and have been seen as an indicator of increased survival time in Epithelial Ovarian Cancer patients.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
15,635 Da
NCBI Official Full Name
CD44
NCBI Official Synonym Full Names
CD44 molecule (Indian blood group)
NCBI Official Symbol
CD44
NCBI Official Synonym Symbols
IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; MGC10468
NCBI Protein Information
CD44 antigen; epican; Hermes antigen; OTTHUMP00000232487; OTTHUMP00000232488; OTTHUMP00000232489; OTTHUMP00000232491; OTTHUMP00000232492; OTTHUMP00000232493; OTTHUMP00000232494; OTTHUMP00000232495; OTTHUMP00000232522; hyaluronate receptor; phagocytic glycoprotein 1; heparan sulfate proteoglycan; cell surface glycoprotein CD44; extracellular matrix receptor III; chondroitin sulfate proteoglycan 8; GP90 lymphocyte homing/adhesion receptor; hematopoietic cell E- and L-selectin ligand; homing function and Indian blood group system
UniProt Protein Name
CD44 antigen (Indian blood group), isoform CRA_g
UniProt Gene Name
CD44
UniProt Entry Name
O95370_HUMAN
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Product Notes
The CD44 cd44 (Catalog #AAA59264) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD44 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD44, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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