SDS-PAGE
(SDS-PAGE Analyis Purified CD54 Mouse Monoclonal Antibody (15.2). Confirmation of Purity and Integrity of Antibody.)
Mouse anti-Human, Pig CD54/ICAM-1 Monoclonal Antibody | anti-ICAM1 antibody
CD54/ICAM-1
Gene Names
ICAM1; BB2; CD54; P3.58
Reactivity
Human, Pig
Applications
Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay, Functional Assay
Purity
Purified Ab with BSA and Azide at 200ug/ml
Synonyms
CD54/ICAM-1, Antibody; CD54/ICAM-1; CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM-1; Intercellular adhesion molecule 1; Ly 47; Major group rhinovirus receptor; MALA2; MyD10; Surface antigen of activated B cells; anti-ICAM1 antibody
Host
Mouse
Reactivity
Human, Pig
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
15.2
Specificity
Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml
Form/Format
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide.
Sequence Length
532
Applicable Applications for anti-ICAM1 antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), FA (Functional Assay)
Positive Control
Raji cells, MOLT 4, HeLa or SW480 cells. Human tonsil.
Immunogen
Human monocytes.
Cellular Localization
Cell Surface
Hu-chromosome Location
19p13.3-p13.2
Preparation and Storage
Store at 2 to 8 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analyis Purified CD54 Mouse Monoclonal Antibody (15.2). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analyis Purified CD54 Mouse Monoclonal Antibody (15.2). Confirmation of Purity and Integrity of Antibody.)
References
1. Hromatka, BS et al. Biol Reprod. 2013 Jun 20;88(6):154. (IHC) 2. Huegel R et al. J Invest Dermatol. 2007 Jan;127(1):65-74. (IC) 3. Johnson, J.P., et al. Leucocyte Typing IV, Oxford Univ. Press, pp 681-683. (FC)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
85-115kDa
NCBI Official Full Name
intercellular adhesion molecule 1
NCBI Official Synonym Full Names
intercellular adhesion molecule 1
NCBI Official Symbol
ICAM1
NCBI Official Synonym Symbols
BB2; CD54; P3.58
NCBI Protein Information
intercellular adhesion molecule 1
UniProt Protein Name
Intercellular adhesion molecule 1
UniProt Gene Name
ICAM1
UniProt Synonym Gene Names
ICAM-1
UniProt Entry Name
ICAM1_HUMAN
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Product Notes
The ICAM1 icam1 (Catalog #AAA215018) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD54/ICAM-1 reacts with Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's CD54/ICAM-1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), FA (Functional Assay). Researchers should empirically determine the suitability of the ICAM1 icam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD54/ICAM-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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