Mouse anti-Human CD56 (NCAM) Monoclonal Antibody
Mouse Anti-Human CD56-PE
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Synonyms
CD56 (NCAM), Antibody; Mouse Anti-Human CD56-PE; Mouse Anti-Human CD56 - Phycoerythrin-Labeled; Mouse Anti-Human CD56 (NCAM); anti-CD56 (NCAM) antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2aκ
Clone Number
MEM 188
Specificity
Human / Porcine CD56; Mr 175-220 kDa
Form/Format
The R-phycoerythrin (R-PE) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent.
Sequence Length
848
Applicable Applications for anti-CD56 (NCAM) antibody
FCM/FACS (Flow Cytometry)
Immunogen
Acute myelogenous leukemia cell line KG-1
Workshop
VI NK26, A055; VII 70077
Preparation and Storage
Store at 2-8°C. Do not freeze!
Related Product Information for anti-CD56 (NCAM) antibody
Description: CD56, an isoform of the neural cell adhesion molecule (NCAM), is a 220 kDa heavily glycosylated type I transmembrane protein. On human hematopoietic cells, its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.
References
1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford.
2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD56 Section, Academic Press, New York, p. 284.
3. Rabinowitz, J.E., U. Rutishauser, and T. Magnuson. 1996. Proc. Natl. Acad. Sci. USA 93:6421.
4. Muller, D., C. Wang, G. Skibo, N. Toni, H. Cremer, V. Calaora, G. Rougon, and J.Z. Kiss. 1996. Neuron 17:413.
2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD56 Section, Academic Press, New York, p. 284.
3. Rabinowitz, J.E., U. Rutishauser, and T. Magnuson. 1996. Proc. Natl. Acad. Sci. USA 93:6421.
4. Muller, D., C. Wang, G. Skibo, N. Toni, H. Cremer, V. Calaora, G. Rougon, and J.Z. Kiss. 1996. Neuron 17:413.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
CD56
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Product Notes
The CD56 (NCAM) (Catalog #AAA78751) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human CD56-PE reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD56 (NCAM) can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD56 (NCAM) for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD56 (NCAM), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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