IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with CD56 Monoclonal Antibody (123C3.D5 + 123A8))
Mouse anti-Human CD56 / NCAM1 / NKH1 Monoclonal Antibody | anti-NCAM1 antibody
CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Mouse Monoclonal Antibody
Gene Names
NCAM1; CD56; NCAM; MSK39
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
CD56 / NCAM1 / NKH1, Antibody; CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Mouse Monoclonal Antibody; NCAM, Leu-19, NKH1, MSK39, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule; anti-NCAM1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
123C3.D5 + 123A8
Specificity
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the nodal and nasal NK/T-cell lymphomas.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
848
Applicable Applications for anti-NCAM1 antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Cellular Localization
Cell Surface
Immunogen
Membrane preparation of a small cell lung carcinoma
Hu-Chromosome Location
11q23.1
Positive Control
Cerebellum, Pancreas, Neuroblastoma
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with CD56 Monoclonal Antibody (123C3.D5 + 123A8))
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with CD56 Monoclonal Antibody (123C3.D5 + 123A8))
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Colon Ganglion stained with CD56 Monoclonal Antibody (123C3.D5 + 123A8))
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Colon Ganglion stained with CD56 Monoclonal Antibody (123C3.D5 + 123A8))
References
Schol DJ; et. al. Int J Cancer. Supplement, 1988, 2:34-40 Michalides R; et. al. International Journal of Cancer. Supplement, 1994, 8:34-7. Gerardy-Schahn R; et. al. Int Journal of Cancer. Supplement, 1994, 8:38-42
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
180; 145; 125kDa
NCBI Official Full Name
neural cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
neural cell adhesion molecule 1
NCBI Official Symbol
NCAM1
NCBI Official Synonym Symbols
CD56; NCAM; MSK39
NCBI Protein Information
neural cell adhesion molecule 1
UniProt Protein Name
Neural cell adhesion molecule 1
UniProt Gene Name
NCAM1
UniProt Synonym Gene Names
NCAM; N-CAM-1; NCAM-1
UniProt Entry Name
NCAM1_HUMAN
Similar Products
Product Notes
The NCAM1 ncam1 (Catalog #AAA62625) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Mouse Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD56 / NCAM1 / NKH1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the NCAM1 ncam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD56 / NCAM1 / NKH1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.