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product-image-AAA12041_APP6.gif Application Data (Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:FITC)

Hamster CD61 Monoclonal Antibody | anti-CD61 antibody

HAMSTER ANTI MOUSE CD61:RPE

Gene Names
Itgb3; CD61; GP3A; INGRB3
Applications
Flow Cytometry, Functional Assay
Synonyms
CD61, Antibody; HAMSTER ANTI MOUSE CD61:RPE; anti-CD61 antibody
Ordering
For Research Use Only!
Host
Hamster
Clonality
Monoclonal
Isotype
IgG
Clone Number
HM beta 3.1
Form/Format
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
Sequence Length
787
Applicable Applications for anti-CD61 antibody
Flow cytometry (FC/FACS)
Application Notes
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
Reconstitution
Reconstitute with 1.0 ml distilled water
Perservative Stabilisers
Immunogen
Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4
Fusion Partners
Target Species
Mouse
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light.
Shelf Life: 12 months from date of reconstitution.

Application Data

(Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:FITC)

product-image-AAA12041_APP6.gif Application Data (Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:FITC)

Application Data

(Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:Biotin)

product-image-AAA12041_APP5.gif Application Data (Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:Biotin)

Application Data

(Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:Alexa Fluor ?488)

product-image-AAA12041_APP4.gif Application Data (Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:Alexa Fluor ?488)

Application Data

(Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:FITC)

product-image-AAA12041_APP3.gif Application Data (Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:FITC)

Application Data

(Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:Alexa Fluor 647)

product-image-AAA12041_APP2.gif Application Data (Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:Alexa Fluor 647)

Application Data

(Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:RPE)

product-image-AAA12041_APP.gif Application Data (Staining of mouse peripheral blood platelets with Hamster anti Mouse CD61:RPE)
Related Product Information for anti-CD61 antibody
Hamster anti Mouse CD61 antibody, clone HM beta 3-1 recognizes the murine integrin beta 3 subunit (CD61), a 90kDa a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin. Hamster anti Mouse CD61 antibody, clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin (Yasuda et al. 1995).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
86,738 Da
NCBI Official Full Name
integrin beta-3
NCBI Official Synonym Full Names
integrin beta 3
NCBI Official Symbol
Itgb3
NCBI Official Synonym Symbols
CD61; GP3A; INGRB3
NCBI Protein Information
integrin beta-3; GPIIIa; platelet gpIIIa; platelet membrane glycoprotein IIIa
UniProt Protein Name
Integrin beta-3
UniProt Gene Name
Itgb3
UniProt Synonym Gene Names
GPIIIa
UniProt Entry Name
ITB3_MOUSE

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Product Notes

The CD61 itgb3 (Catalog #AAA12041) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD61 can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR. Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10. Researchers should empirically determine the suitability of the CD61 itgb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD61, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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