IHC (Immunohiostchemistry)
Mouse anti-Human CD63 Monoclonal Antibody | anti-CD63 antibody
CD63
Gene Names
CD63; MLA1; ME491; LAMP-3; OMA81H; TSPAN30
Reactivity
Human
Synonyms
CD63, Antibody; CD63; anti-CD63 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1/K
Clone Number
NKI/C3
Form/Format
CD63 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Malignant Melanoma
Localization
Cytoplasmic, Membranous
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
Dilution Info
Dilution Info
Related Product Information for anti-CD63 antibody
The protein encoded by CD63 gene is a member of the transmembrane-4 superfamily, also known as the tet-raspanin family, and mediates signal-transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell-surface glycoprotein that is known to complex with integrins. It may function as a blood-platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak Syndrome. This gene has been associated with tumor progression. CD63 is a good marker for flow-cytometric quantification of in vitro-activated basophils for identification of IgE-mediated allergy. The test is commonly designated as a basophil activation test. Anti-CD63 reacts with a 53 kDa protein. The antigen was originally designated as a lysosomal membrane protein characterized as an activation-dependent platelet surface antigen. In fact, the CD63 antigen has a diverse distribution on the surface and in the cytoplasm of many cell types including lymphoid, myeloid and endothelial cells and Melanoma. It is weakly expressed in granulocytes, B and T-cells. It has been quite useful in identifying Malignant Melanoma. CD63 is thought to be associated with the early stages of Melanoma tumor progression (in regulation of motility and adhesion of Melanoma cells).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,637 Da
NCBI Official Full Name
CD63 antigen isoform B
NCBI Official Synonym Full Names
CD63 molecule
NCBI Official Symbol
CD63
NCBI Official Synonym Symbols
MLA1; ME491; LAMP-3; OMA81H; TSPAN30
NCBI Protein Information
CD63 antigen; tspan-30; granulophysin; tetraspanin-30; melanoma 1 antigen; melanoma-associated antigen MLA1; CD63 antigen (melanoma 1 antigen); melanoma-associated antigen ME491; ocular melanoma-associated antigen; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3
UniProt Protein Name
CD63 antigen
UniProt Gene Name
CD63
UniProt Synonym Gene Names
MLA1; TSPAN30
UniProt Entry Name
CD63_HUMAN
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Product Notes
The CD63 cd63 (Catalog #AAA59248) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD63 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD63, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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