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product-image-AAA315374_IF13.jpg IF (Immunofluorescence) (Immunofluorescent analysis of NIH/3T3 cells, using CDK4 Antibody.)

CDK4 recombinant antibody

CDK4 Rabbit mAb

Gene Names
CDK4; CMM3; PSK-J3
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Western Blot
Purity
Affinity-chromatography
Synonyms
CDK4, Recombinant Antibody; CDK4 Rabbit mAb; Cyclin-dependent kinase 4; Cell division protein kinase 4; PSK-J3; PSKJ3; CDK4; Crk3; CMM 3; CDK4 recombinant antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
Rabbit IgG
Specificity
CDK4 Antibody detects endogenous levels of CDK4
Purity/Purification
Affinity-chromatography
Form/Format
Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applicable Applications for CDK4 recombinant antibody
IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human CDK4
Preparation and Storage
Store at +4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.

IF (Immunofluorescence)

(Immunofluorescent analysis of NIH/3T3 cells, using CDK4 Antibody.)

product-image-AAA315374_IF13.jpg IF (Immunofluorescence) (Immunofluorescent analysis of NIH/3T3 cells, using CDK4 Antibody.)

WB (Western Blot)

(Western blot analysis of CDK4 expression in HeLa cell lysate.)

product-image-AAA315374_WB15.jpg WB (Western Blot) (Western blot analysis of CDK4 expression in HeLa cell lysate.)
Related Product Information for CDK4 recombinant antibody
Cyclin-dependent kinase activity is regulated by T-loop phosphorylation (Thr172 in the case of CDK4), by the abundance of their cyclin partners, and by association with CDK inhibitors of the Cip/Kip or INK family of proteins. The active complex of CDK4/cyclin D targets the retinoblastoma protein for phosphorylation, allowing the release of E2F transcription factors that activate G1/S-phase gene expression.
Product Categories/Family for CDK4 recombinant antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34kDa
NCBI Official Full Name
cyclin-dependent kinase 4
NCBI Official Synonym Full Names
cyclin-dependent kinase 4
NCBI Official Symbol
CDK4
NCBI Official Synonym Symbols
CMM3; PSK-J3
NCBI Protein Information
cyclin-dependent kinase 4; cell division protein kinase 4
UniProt Protein Name
Cyclin-dependent kinase 4
UniProt Gene Name
CDK4
UniProt Entry Name
CDK4_HUMAN

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Product Notes

The CDK4 cdk4 (Catalog #AAA315374) is a Recombinant Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDK4 Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CDK4 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CDK4 cdk4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK4, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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