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product-image-AAA312637_ICC10.jpg ICC (Immunocytochemistry) (ICC staining CPS1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Rabbit CPS1 Monoclonal Antibody | anti-CPS1 antibody

CPS1 Antibody

Gene Names
CPS1; PHN; CPSASE1
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
CPS1, Antibody; CPS1 Antibody; Carbamoyl phosphate synthase [ammonia] antibody; Carbamoyl phosphate synthase [ammonia] mitochondrial antibody; Carbamoyl phosphate synthase antibody; Carbamoyl phosphate synthetase 1 antibody; Carbamoyl phosphate synthetase 1 mitochondrial antibody; Carbamoyl phosphate synthetase I antibody; Carbamoyl-phosphate synthase [ammonia] antibody; Carbamoyl-phosphate synthetase I antibody; Carbamoylphosphate synthase antibody; Carbamoylphosphate synthetase 1 antibody; Carbamoylphosphate synthetase I antibody; CPS 1 antibody; Cps1 antibody; CPSase 1 antibody; CPSase I antibody; CPSASE1 antibody; CPSM_HUMAN antibody; mitochondrial antibody; MS738 antibody; anti-CPS1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
JB40-33
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-CPS1 antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

ICC (Immunocytochemistry)

(ICC staining CPS1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

product-image-AAA312637_ICC10.jpg ICC (Immunocytochemistry) (ICC staining CPS1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-CPS1 antibody. Counter stained with hematoxylin.)

product-image-AAA312637_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-CPS1 antibody. Counter stained with hematoxylin.)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CPS1 antibody. Counter stained with hematoxylin.)

product-image-AAA312637_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CPS1 antibody. Counter stained with hematoxylin.)

WB (Western Blot)

(Western blot analysis of CPS1 on SiHa cell using anti-CPS1 antibody at 1/500 dilution.)

product-image-AAA312637_WB15.jpg WB (Western Blot) (Western blot analysis of CPS1 on SiHa cell using anti-CPS1 antibody at 1/500 dilution.)
Related Product Information for anti-CPS1 antibody
The multicomplex protein, carbamoyl-phosphate synthetase-aspartate carbamoyl transferase-dihydro-orotase (CAD), consists of three distinct proteins, carbamoyl phosphate synthetase 2 (CPS2), aspartate transcarbamylase, and dihydro-orotase, which catalyze the second and third steps of pyrimidine biosynthesis. CAD is allosterically regulated by the phosphorylation of CPS2 by cyclic AMP-dependent protein kinase, and this activation enables CPS2 to catalyze the rate-limiting step of pyrimidine synthesis. CAD is expressed in brain and skeletal muscle. A related protein, carbamoyl phosphate synthetase 1 (CPS1) is expressed in liver. CPS1 catalyzes the rate-limiting step in the urea cycle, and deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia.
Product Categories/Family for anti-CPS1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
165,650 Da
NCBI Official Full Name
carbamoyl-phosphate synthase
NCBI Official Synonym Full Names
carbamoyl-phosphate synthase 1, mitochondrial
NCBI Official Symbol
CPS1
NCBI Official Synonym Symbols
PHN; CPSASE1
NCBI Protein Information
carbamoyl-phosphate synthase [ammonia], mitochondrial; carbamoyl-phosphate synthase [ammonia], mitochondrial; carbamoylphosphate synthetase I
UniProt Protein Name
Carbamoyl-phosphate synthase [ammonia], mitochondrial
UniProt Gene Name
CPS1
UniProt Synonym Gene Names
CPSase I
UniProt Entry Name
CPSM_HUMAN

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Product Notes

The CPS1 cps1 (Catalog #AAA312637) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CPS1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CPS1 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CPS1 cps1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPS1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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