IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissues using CRYAB antibody.)
Mouse CRYAB Monoclonal Antibody | anti-CRYAB antibody
CRYAB antibody
Applications
Western Blot, Immunohistochemistry, ELISA
Synonyms
CRYAB, Antibody; CRYAB antibody; Monoclonal CRYAB; Anti-CRYAB; Crystallin alpha polypeptide 2; Heat shock protein beta 5; Renal carcinoma protein NY-REN-27; Alpha crystallin B chain; Alpha(B) crystallin; CTPP2; Crystallin alpha B; AACRYA; Heat shock protein beta-5; Heat shock 20 kD like protein; Renal carcinoma protein NY REN 27; CTPP 2; HspB5; NY REN 27 protein; CRYA2; Rosenthal fiber component; anti-CRYAB antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
1D11C6E6
Form/Format
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
175
Applicable Applications for anti-CRYAB antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Biological Significance
Alpha crystallins are composed of two gene products ; alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein(sHSP also known as the HSP20). They act as molecular chaperones and hold them in in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-B is expressed widely in many tissues and organs and occurs in many neurological diseases.
Cross-Reactivity
Human
Immunogen
CRYAB antibody was raised in Mouse using a purified recombinant fragment of CRYAB(aa1-175) expressed in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissues using CRYAB antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissues using CRYAB antibody.)
WB (Western Blot)
(Western Blot showing CRYAB antibody used against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY CRYAB cDNA (2).)
WB (Western Blot)
(Western Blot showing CRYAB antibody used against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY CRYAB cDNA (2).)
Related Product Information for anti-CRYAB antibody
Mouse monoclonal CRYAB antibody
Product Categories/Family for anti-CRYAB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
20,129 Da
NCBI Official Full Name
CRYAB
NCBI Official Symbol
CRYAB
NCBI Protein Information
crystallin, alpha B; Alpha(B)-crystallin; Alpha-crystallin B chain
UniProt Protein Name
Alpha-crystallin B chain
UniProt Gene Name
CRYAB
UniProt Entry Name
CRYAB_PIG
Similar Products
Product Notes
The CRYAB cryab (Catalog #AAA106286) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CRYAB can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the CRYAB cryab for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRYAB, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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