IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human prostate stained with Cytokeratin 14 Mouse Monoclonal Antibody (KRT14/4133).)
Mouse anti-Human Cytokeratin 14 (KRT14) Monoclonal Antibody | anti-KRT14 antibody
Cytokeratin 14 (KRT14) (Squamous Cell Marker) Mouse Monoclonal Antibody [Clone KRT14/4133]
Gene Names
KRT14; K14; NFJ; CK14; EBS3; EBS4
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Cytokeratin 14 (KRT14), Antibody; Cytokeratin 14 (KRT14) (Squamous Cell Marker) Mouse Monoclonal Antibody [Clone KRT14/4133]; Cytokeratin 14 (KRT14) (Squamous Cell Marker); CK-14; Dowling Meara; ebs3; ebs4; Epidermolysis Bullosa Simplex; Keratin Type I Cytoskeletal 14; Koebner; NFJ; anti-KRT14 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2b, kappa
Clone Number
KRT14/4133
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-KRT14 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant fragment (around aa351-472) of human KRT14 protein (exact sequence is proprietary)
Cellular Localization
Cytoplasmic
Positive Control
Human skin or squamous cell carcinoma tissue.
Hu-chromosome Location
17q21.2
Unigene
6545380
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human prostate stained with Cytokeratin 14 Mouse Monoclonal Antibody (KRT14/4133).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human prostate stained with Cytokeratin 14 Mouse Monoclonal Antibody (KRT14/4133).)
Related Product Information for anti-KRT14 antibody
Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
472
NCBI Official Full Name
Keratin, type I cytoskeletal 14
NCBI Official Synonym Full Names
keratin 14
NCBI Official Symbol
KRT14
NCBI Official Synonym Symbols
K14; NFJ; CK14; EBS3; EBS4
NCBI Protein Information
keratin, type I cytoskeletal 14; CK-14; keratin-14; cytokeratin 14; cytokeratin-14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)
UniProt Protein Name
Keratin, type I cytoskeletal 14
UniProt Gene Name
KRT14
UniProt Synonym Gene Names
CK-14; K14
UniProt Entry Name
K1C14_HUMAN
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Product Notes
The KRT14 krt14 (Catalog #AAA215769) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 14 (KRT14) (Squamous Cell Marker) Mouse Monoclonal Antibody [Clone KRT14/4133] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin 14 (KRT14) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the KRT14 krt14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 14 (KRT14), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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