IHC (Immunohiostchemistry)
Mouse anti-Human Cytokeratin HMW, AE3 Monoclonal Antibody
Cytokeratin HMW, AE3
Reactivity
Human
Synonyms
Cytokeratin HMW, AE3, Antibody; Cytokeratin HMW, AE3; anti-Cytokeratin HMW, AE3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
AE3
Form/Format
Cytokeratin HMW AE3 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Prostate, Bladder, Salivary Gland
Localization
Cytoplasmic
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
Dilution Info
Dilution Info
Related Product Information for anti-Cytokeratin HMW, AE3 antibody
Cytokeratins are intermediate-filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types of cytokeratins: the low-weight, acidic Type I cytokeratins and the high-weight, basic or neutral Type II cytokeratins. Cytokeratins are usually found in pairs comprising a Type I cytokeratin and a Type II cytokeratin. Expression of these cytokeratins is frequently organ or tissue-specific. Cytokeratin, High Molecular Weight AE3 (HMW, CK 8) is capable of recognizing all basic cytokeratins; therefore, it is a broadly reactive antibody staining most epithelia and their neoplasms. Cytokeratin HMW/AE3 stains normal and neoplastic cells of epithelial origin. CK HMW is primarily found in the non-squamous epithelia and is present in the majority of Adenocarcinomas and Ductal Carcinomas. It is absent in Squamous Cell Carcinomas. Hepatocellular Carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18.
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Product Notes
The Cytokeratin HMW, AE3 (Catalog #AAA59212) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin HMW, AE3 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Cytokeratin HMW, AE3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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