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IHC (Immunohistochemistry)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, IHC(P)IHC(P): Human Mammary Cancer Tissue)
Mouse anti-Human, Rat Cytokeratin Peptide 18 Monoclonal Antibody | anti-KRT18 antibody
Anti-Cytokeratin Peptide 18 antibody (monoclonal)
Gene Names
KRT18; K18; CYK18
Reactivity
Human, Rat
Applications
Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Ascites
Synonyms
Cytokeratin Peptide 18, Antibody; Anti-Cytokeratin Peptide 18 antibody (monoclonal); Keratin, type I cytoskeletal 18; keratin 18; K18; Keratin-18; CK-18; Cytokeratin-18; CYK18; Cell proliferation-inducing gene 46 protein; anti-KRT18 antibody
Host
Mouse
Reactivity
Human, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
CK-18
Purity/Purification
Ascites
Form/Format
Lyophilized
Sequence Length
430
Applicable Applications for anti-KRT18 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.
Contents
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Reconstitution
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemistry)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohistochemisry)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, IHC(P)IHC(P): Human Rectal Cancer Tissue)
IHC (Immunohistochemisry)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, IHC(P)IHC(P): Human Rectal Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, Western blottingWB: MCF-7 Cell Lysate)
WB (Western Blot)
(Anti-Cytokeratin Peptide 18 antibody (monoclonal), AAA44913, Western blottingWB: MCF-7 Cell Lysate)
Related Product Information for anti-KRT18 antibody
Description: Mouse IgG monoclonal antibody for Cytokeratin Peptide 18, keratin 18 (KRT18) detection. Tested with WB, IHC-P, IHC-F in Human, rat. No cross reactivity with other proteins. Uniprot ID: P05783
Background: Intermediate filaments(IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18(KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosis.
Background: Intermediate filaments(IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18(KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
48,058 Da
NCBI Official Full Name
Keratin, type I cytoskeletal 18
NCBI Official Synonym Full Names
keratin 18
NCBI Official Symbol
KRT18
NCBI Official Synonym Symbols
K18; CYK18
NCBI Protein Information
keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein
UniProt Protein Name
Keratin, type I cytoskeletal 18
UniProt Gene Name
KRT18
UniProt Synonym Gene Names
CYK18; CK-18; K18
UniProt Entry Name
K1C18_HUMAN
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Product Notes
The KRT18 krt18 (Catalog #AAA44913) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Cytokeratin Peptide 18 antibody (monoclonal) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin Peptide 18 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KRT18 krt18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin Peptide 18, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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