IHC (Immunohiostchemistry)
(RAT DLG4 Antibody (C-term)(Ascites) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RAT DLG4 Antibody (C-term)(Ascites) for immunohistochemistry. Clinical relevance has not been evaluated.)
Mouse anti-Human, mouse DLG4 Monoclonal Antibody | anti-Dlg4 antibody
DLG4 Antibody (C-term) (Rat) (Ascites)
Gene Names
Dlg4; Dlgh4; PSD95; Sap90
Reactivity
Human, mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Synonyms
DLG4, Antibody; DLG4 Antibody (C-term) (Rat) (Ascites); Disks large homolog 4; Postsynaptic density protein 95; PSD-95; Synapse-associated protein 90; SAP-90; SAP90; Dlg4; Dlgh4; Psd95; anti-Dlg4 antibody
Host
Mouse
Reactivity
Human, mouse
Clonality
Monoclonal
Isotype
IgM
Clone Number
127CT15.8.20
Specificity
This DLG4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 677-706 amino acids from the C-terminal region of human DLG4.
Form/Format
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Sequence Positions
677-706
Sequence Length
724
Applicable Applications for anti-Dlg4 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
RAT
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(RAT DLG4 Antibody (C-term)(Ascites) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RAT DLG4 Antibody (C-term)(Ascites) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(RAT DLG4 Antibody (C-term)(Ascites) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RAT DLG4 Antibody (C-term)(Ascites) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of RAT DLG4 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane).DLG4 (arrow) was detected using the purified Mab.(1:100))
WB (Western Blot)
(Western blot analysis of RAT DLG4 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane).DLG4 (arrow) was detected using the purified Mab.(1:100))
Related Product Information for anti-Dlg4 antibody
a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway [RGD]
References
SAP102 is a highly mobile MAGUK in spines. Zheng CY, et al. J Neurosci, 2010 Mar 31. PMID 20357126. Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation. de Arce KP, et al. J Neurosci, 2010 Mar 10. PMID 20220006. Transduced PDZ1 domain of PSD-95 decreases Src phosphorylation and increases nNOS (Ser847) phosphorylation contributing to neuroprotection after cerebral ischemia. Wang WW, et al. Brain Res, 2010 Apr 30. PMID 20197063. Hidden dynamic allostery in a PDZ domain. Petit CM, et al. Proc Natl Acad Sci U S A, 2009 Oct 27. PMID 19828436. Integrin-linked kinase is involved in cocaine sensitization by regulating PSD-95 and synapsin I expression and GluR1 Ser845 phosphorylation. Chen Q, et al. J Mol Neurosci, 2010 Mar. PMID 19629758.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80465
NCBI Official Full Name
disks large homolog 4
NCBI Official Synonym Full Names
discs, large homolog 4 (Drosophila)
NCBI Official Symbol
Dlg4
NCBI Official Synonym Symbols
Dlgh4; PSD95; Sap90
NCBI Protein Information
disks large homolog 4
UniProt Protein Name
Disks large homolog 4
UniProt Gene Name
Dlg4
UniProt Synonym Gene Names
Dlgh4; Psd95; PSD-95; SAP-90; SAP90
UniProt Entry Name
DLG4_RAT
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Product Notes
The Dlg4 dlg4 (Catalog #AAA283477) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 677-706. The DLG4 Antibody (C-term) (Rat) (Ascites) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DLG4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the Dlg4 dlg4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLG4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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