SEC-HPLC
(The purity of this product is >95% as determined by SEC-MALS.)
anti-Human Donanemab Monoclonal Antibody | anti-APP antibody
Research Grade Donanemab
Gene Names
APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
Reactivity
Human
Applications
Research Grade Biosimilar
Purity
>95%, by SDS-PAGE; Protein A or G purified from cell culture supernatant.
Synonyms
Donanemab, Antibody; Research Grade Donanemab; LY3002813; AICD-57; A4; Beta-CTF; Protease nexin-II; Gamma-CTF(50); ABPP; S-APP-beta; APP; Abeta40; Abeta42; AID(59); Amyloid intracellular domain 59; AID(57); S-APP-alpha; Gamma-CTF(59); Beta-secretase C-terminal fragment; Amyloid-beta precursor protein; Amyloid precursor protein; Beta-APP42; PreA4; Alzheimer disease amyloid protein; APPI; PN-II; AICD-59; Alpha-secretase C-terminal fragment; Amyloid-beta A4 protein; Amyloid intracellular domain 57; CVAP; Amyloid intracellular domain 50; Beta-APP40; AD1; Cerebral vascular amyloid peptide; AID(50); Alpha-CTF; Gamma-CTF(57); AICD-50; anti-APP antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1-kappa
Purity/Purification
>95%, by SDS-PAGE; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. 0.01M PBS, pH7.4
Concentration
6.06 mg/ml (varies by lot)
Applicable Applications for anti-APP antibody
Research Grade Biosimilar
Expression System
Mammalian cells
Host Species
Humanized
CAS
1931944-80-7
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SEC-HPLC
(The purity of this product is >95% as determined by SEC-MALS.)
SEC-HPLC
(The purity of this product is >95% as determined by SEC-MALS.)
SDS-PAGE
(SDS PAGE for Donanemab)
SDS-PAGE
(SDS PAGE for Donanemab)
Product Categories/Family for anti-APP antibody
References
Donanemab in Early Alzheimer's Disease, PMID: 34379933
Donanemab (LY3002813) dose-escalation study in Alzheimer's disease, PMID: 33614890
Donanemab in Early Alzheimer's Disease. Reply, PMID: 34379934
Brain volume loss due to donanemab, PMID: 34224184
Still grasping at straws: donanemab in Alzheimer's disease, PMID: 34162295
Donanemab (LY3002813) dose-escalation study in Alzheimer's disease, PMID: 33614890
Donanemab in Early Alzheimer's Disease. Reply, PMID: 34379934
Brain volume loss due to donanemab, PMID: 34224184
Still grasping at straws: donanemab in Alzheimer's disease, PMID: 34162295
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
amyloid beta A4 protein isoform a
NCBI Official Synonym Full Names
amyloid beta (A4) precursor protein
NCBI Official Symbol
APP
NCBI Official Synonym Symbols
AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
NCBI Protein Information
amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide
UniProt Protein Name
Amyloid beta A4 protein
UniProt Gene Name
APP
UniProt Synonym Gene Names
A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)
UniProt Entry Name
A4_HUMAN
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Product Notes
The APP app (Catalog #AAA18886) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Donanemab reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Donanemab can be used in a range of immunoassay formats including, but not limited to, Research Grade Biosimilar. Researchers should empirically determine the suitability of the APP app for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Donanemab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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