IF (Immunofluorescence)
Mouse anti-Rat Dopamine Transporter Monoclonal Antibody | anti-SLC6A3 antibody
Mouse Anti-Dopamine Transporter [6V-23-23]
Gene Names
SLC6A3; DAT; DAT1; PKDYS
Reactivity
Rat
Applications
Immunofluorescence, Western Blot
Purity
Protein A affinity-purified
Synonyms
Dopamine Transporter, Antibody; Mouse Anti-Dopamine Transporter [6V-23-23]; DA transporter antibody; DAT 1 antibody; DAT antibody; DAT1 antibody; Dopamine transporter antibody; SC6A3_HUMAN antibody; anti-SLC6A3 antibody
Host
Mouse
Reactivity
Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6V-23-23
Specificity
Rat DAT; cross reacts with mouse DAT (other species not tested); little to no human reactivity.
Purity/Purification
Protein A affinity-purified
Form/Format
Constituted in 0.02M Potassium Phosphate, 0.15M sodium chloride, 0.1% sodium azide; pH 7.2.
Concentration
1.62mg/ml (varies by lot)
Sequence Length
620
Applicable Applications for anti-SLC6A3 antibody
IF (Immunofluorescence), WB (Western Blot)
Preparation and Storage
Store at 4°C for one month, or in small aliquots at -20°C for longer periods. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.
IF (Immunofluorescence)
IF (Immunofluorescence)
References
Gaffaney JD, Vaughan RA. Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Mol Pharmacol. 2004 Mar;65(3):692-701. PUBMED Cremona M.L.et al. Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT. Nat Neurosci. 2011; 14(4):469-77 PUBMED Foster JD, et al. Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. J Biol Chem. 2011; 286(7):5175-86 PUBMED
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
68,495 Da
NCBI Official Full Name
dopamine transporter
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter), member 3
NCBI Official Symbol
SLC6A3
NCBI Official Synonym Symbols
DAT; DAT1; PKDYS
NCBI Protein Information
sodium-dependent dopamine transporter; DA transporter; dopamine transporter 1; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
UniProt Protein Name
Sodium-dependent dopamine transporter
UniProt Gene Name
SLC6A3
UniProt Synonym Gene Names
DAT1; DA transporter; DAT
UniProt Entry Name
SC6A3_HUMAN
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Product Notes
The SLC6A3 slc6a3 (Catalog #AAA59518) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Dopamine Transporter [6V-23-23] reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Dopamine Transporter can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the SLC6A3 slc6a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dopamine Transporter, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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