EGFR domain III Recombinant Antibody | EGFR recombinant antibody
Anti-EGFR domain III [h-R3 (Nimotuzumab)]
Gene Names
EGFR; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
Reactivity
Human
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Protein A Affinity Purified
Synonyms
EGFR domain III, Recombinant Antibody; Anti-EGFR domain III [h-R3 (Nimotuzumab)]; ERBB; ERBB1; HER1; PIG61; mENA; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor; EGFR recombinant antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
Human IgG1, Kappa
Clone Number
h-R3
Specificity
Binds to human EGFR domain III at a site distinct from antibody 7A7 (Ab00134) (Talavera et al. 2011)
Purity/Purification
Protein A Affinity Purified
Form/Format
PBS with 0.02% Proclin 300
Concentration
1 mg/ml (varies by lot)
Sequence Length
1210
Applicable Applications for EGFR recombinant antibody
IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), Blocking
Immunogen
This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors.
Note
Describes the generation and characterisation of the R3 antibody from which h-R3 was generated by humanisation.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for EGFR recombinant antibody
Recombinant monoclonal antibody to EGFR domain III. Manufactured using a proprietary Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody h-R3 (Nimotuzumab).
This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors.
This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors.
Product Categories/Family for EGFR recombinant antibody
References
Fernandez et al. A new monoclonal antibody for detection of EGF-receptors in western blots and paraffin-embedded tissue sections. J Cell Biochem. 1992 Jun; 49(2):157-65. PMID:1400622
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
epidermal growth factor receptor isoform a
NCBI Official Synonym Full Names
epidermal growth factor receptor
NCBI Official Symbol
EGFR
NCBI Official Synonym Symbols
ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
NCBI Protein Information
epidermal growth factor receptor
UniProt Protein Name
Epidermal growth factor receptor
UniProt Gene Name
EGFR
UniProt Synonym Gene Names
ERBB; ERBB1; HER1
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Product Notes
The EGFR egfr (Catalog #AAA72002) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-EGFR domain III [h-R3 (Nimotuzumab)] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EGFR domain III can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), Blocking. Researchers should empirically determine the suitability of the EGFR egfr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EGFR domain III, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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