IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue with Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody at dilution of 1:200)
Mouse ERK 1/2 Monoclonal Antibody | anti-ERK 1/2 antibody
Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody
Gene Names
MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Protein A Purification
Synonyms
ERK 1/2, Antibody; Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody; MAPK1/MAPK3; anti-ERK 1/2 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
4D4
Purity/Purification
Protein A Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
357
Applicable Applications for anti-ERK 1/2 antibody
IHC (Immunohistochemistry)
Immunogen
Synthetic Peptide of Phospho-ERK 1/2 (Tyr222/205)
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue with Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody at dilution of 1:200)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue with Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody at dilution of 1:200)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human colon carcinoma tissue with Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody at dilution of 1:200)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human colon carcinoma tissue with Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody at dilution of 1:200)
Related Product Information for anti-ERK 1/2 antibody
Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
Product Categories/Family for anti-ERK 1/2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,088 Da
NCBI Official Full Name
mitogen-activated protein kinase 3 isoform 2
NCBI Official Synonym Full Names
mitogen-activated protein kinase 3
NCBI Official Symbol
MAPK3
NCBI Official Synonym Symbols
ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK
NCBI Protein Information
mitogen-activated protein kinase 3
UniProt Protein Name
Mitogen-activated protein kinase 3
UniProt Gene Name
MAPK3
UniProt Synonym Gene Names
ERK1; PRKM3; MAP kinase 3; MAPK 3; ERK-1; p44-MAPK
Similar Products
Product Notes
The ERK 1/2 mapk3 (Catalog #AAA174003) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ERK 1/2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the ERK 1/2 mapk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERK 1/2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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