WB (Western Blot)
(K-562 cells were subjected to SDS PAGE followed by western blot with AAA102795 (FGFR1 Antibody) at dilution of 1:1000)
Mouse FGFR1 Monoclonal Antibody | anti-FGFR1 antibody
anti- FGFR1 antibody
Gene Names
FGFR1; CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1
Reactivity
Human, Mouse; Other species are not tested.
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
>95% as determined by SDS-PAGE; Protein A+G purification
Synonyms
FGFR1, Antibody; anti- FGFR1 antibody; BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR; anti-FGFR1 antibody
Host
Mouse
Reactivity
Human, Mouse; Other species are not tested.
Clonality
Monoclonal
Isotype
IgG2a
Specificity
Please decide the specificity by homology.
Purity/Purification
>95% as determined by SDS-PAGE; Protein A+G purification
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Applicable Applications for anti-FGFR1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Fibroblast growth factor receptor 1
Preparation and Storage
-20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
WB (Western Blot)
(K-562 cells were subjected to SDS PAGE followed by western blot with AAA102795 (FGFR1 Antibody) at dilution of 1:1000)
WB (Western Blot)
(K-562 cells were subjected to SDS PAGE followed by western blot with AAA102795 (FGFR1 Antibody) at dilution of 1:1000)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using AAA102795 (FGFR1 Antibody) at dilution of 1:200)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using AAA102795 (FGFR1 Antibody) at dilution of 1:200)
Related Product Information for anti-FGFR1 antibody
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
90 kDa
NCBI Official Full Name
fibroblast growth factor receptor 1 isoform 2
NCBI Official Synonym Full Names
fibroblast growth factor receptor 1
NCBI Official Symbol
FGFR1
NCBI Official Synonym Symbols
CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1
NCBI Protein Information
fibroblast growth factor receptor 1
UniProt Protein Name
Fibroblast growth factor receptor 1
UniProt Gene Name
FGFR1
UniProt Synonym Gene Names
BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; FGFR-1; BFGFR; bFGF-R-1; FLT-2
UniProt Entry Name
FGFR1_HUMAN
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Product Notes
The FGFR1 fgfr1 (Catalog #AAA102795) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The anti- FGFR1 antibody reacts with Human, Mouse; Other species are not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's FGFR1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FGFR1 fgfr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGFR1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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