SDS-PAGE
(SDS PAGE for Figitumumab)
anti-Human Figitumumab Monoclonal Antibody | anti-IGF1R antibody
Research Grade Figitumumab
Gene Names
IGF1R; IGFR; CD221; IGFIR; JTK13
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Figitumumab, Antibody; Research Grade Figitumumab; CP-751871; CD221; Insulin-like growth factor 1 receptor; IGF1R; Insulin-like growth factor I receptor; IGF-I receptor; anti-IGF1R antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
Host Species
Human
CAS
943453-46-1
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
(SDS PAGE for Figitumumab)
SDS-PAGE
(SDS PAGE for Figitumumab)
Bioactivity
(Detects Human CD221/IGF1R in direct ELISAs.)
Bioactivity
(Detects Human CD221/IGF1R in direct ELISAs.)
Product Categories/Family for anti-IGF1R antibody
References
Development of the monoclonal antibody figitumumab, targeting the insulin-like growth factor-1 receptor, for the treatment of patients with non-small-cell lung cancer, PMID: 19632947
Retraction. Pre-treatment levels of circulating free IGF-1 identify NSCLC patients who derive clinical benefit from figitumumab, PMID: 23211971
Figitumumab combined with carboplatin and paclitaxel in treatment-naïve Japanese patients with advanced non-small cell lung cancer, PMID: 21748299
Figitumumab in patients with refractory metastatic colorectal cancer previously treated with standard therapies: a nonrandomized, open-label, phase II trial, PMID: 24488322
Update of IGF-1 receptor inhibitor (ganitumab, dalotuzumab, cixutumumab, teprotumumab and figitumumab) effects on cancer therapy, PMID: 28427155
Retraction. Pre-treatment levels of circulating free IGF-1 identify NSCLC patients who derive clinical benefit from figitumumab, PMID: 23211971
Figitumumab combined with carboplatin and paclitaxel in treatment-naïve Japanese patients with advanced non-small cell lung cancer, PMID: 21748299
Figitumumab in patients with refractory metastatic colorectal cancer previously treated with standard therapies: a nonrandomized, open-label, phase II trial, PMID: 24488322
Update of IGF-1 receptor inhibitor (ganitumab, dalotuzumab, cixutumumab, teprotumumab and figitumumab) effects on cancer therapy, PMID: 28427155
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
154,793 Da
NCBI Official Full Name
insulin-like growth factor 1 receptor
NCBI Official Synonym Full Names
insulin-like growth factor 1 receptor
NCBI Official Symbol
IGF1R
NCBI Official Synonym Symbols
IGFR; CD221; IGFIR; JTK13
NCBI Protein Information
insulin-like growth factor 1 receptor; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor
UniProt Protein Name
Insulin-like growth factor 1 receptor
UniProt Gene Name
IGF1R
UniProt Synonym Gene Names
IGF-I receptor
UniProt Entry Name
IGF1R_HUMAN
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Product Notes
The IGF1R igf1r (Catalog #AAA120021) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Figitumumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Figitumumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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