IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-FTO antibody. Counter stained with hematoxylin.)
Rabbit anti-Human FTO Monoclonal Antibody | anti-FTO antibody
FTO Antibody
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, Immunocytochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
FTO, Antibody; FTO Antibody; AlkB homolog 9 antibody; ALKBH9 antibody; Alpha-ketoglutarate-dependent dioxygenase FTO antibody; AW743446 antibody; Fat mass and obesity-associated protein antibody; FATSO; MOUSE; HOMOLOG OF antibody; Fto antibody; FTO_HUMAN antibody; GDFD antibody; KIAA1752 antibody; mKIAA1752 antibody; Protein fatso antibody; anti-FTO antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-FTO antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-FTO antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-FTO antibody. Counter stained with hematoxylin.)
WB (Western Blot)
(Western blot analysis of FTO on different lysates using anti-FTO antibody at 1/1, 000 dilution. Positive control: Lane 1: Human fetal brain tissue Lane 2: HepG2 Lane 3: 293)
WB (Western Blot)
(Western blot analysis of FTO on different lysates using anti-FTO antibody at 1/1, 000 dilution. Positive control: Lane 1: Human fetal brain tissue Lane 2: HepG2 Lane 3: 293)
Related Product Information for anti-FTO antibody
FTO, also known as Fatso or KIAA1752, is a 505 amino acid protein that has an N-terminal nuclear localization signal. Expressed in a variety of tissues, with highest levels present in brain and pancreatic tissue, Fatso exists as four alternatively spliced isoforms, one of which is associated with a predisposition to childhood and adult obesity. Due to its involvement in the development of obesity, Fatso is associated with an increased BMI and may be involved in the pathogenesis of type 2 diabetes. The gene encoding Fatso maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Product Categories/Family for anti-FTO antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
505
NCBI Official Full Name
alpha-ketoglutarate-dependent dioxygenase FTO
NCBI Official Synonym Full Names
fat mass and obesity associated
NCBI Official Symbol
FTO
NCBI Protein Information
alpha-ketoglutarate-dependent dioxygenase FTO; protein fto; fat mass and obesity-associated protein
UniProt Protein Name
Alpha-ketoglutarate-dependent dioxygenase FTO
UniProt Gene Name
FTO
UniProt Synonym Gene Names
KIAA1752
UniProt Entry Name
FTO_HUMAN
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Product Notes
The FTO fto (Catalog #AAA312555) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FTO Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FTO can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the FTO fto for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FTO, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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