SDS-PAGE
(SDS PAGE for Ganitumab)
Homo sapiens anti-Human Ganitumab Monoclonal Antibody | anti-IGF1R antibody
Research Grade Ganitumab
Gene Names
IGF1R; IGFR; CD221; IGFIR; JTK13
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Ganitumab, Antibody; Research Grade Ganitumab; AMG 479; CD221; Insulin-like growth factor 1 receptor; IGF1R; Insulin-like growth factor I receptor; IGF-I receptor; anti-IGF1R antibody
Host
Homo sapiens
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. 0.01M PBS, pH7.4
Concentration
9.7 mg/ml (varies by lot)
Expression System
Mammalian cells
CAS
905703-97-1
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
(SDS PAGE for Ganitumab)
SDS-PAGE
(SDS PAGE for Ganitumab)
Product Categories/Family for anti-IGF1R antibody
References
Ganitumab (AMG 479) inhibits IGF-II-dependent ovarian cancer growth and potentiates platinum-based chemotherapy, PMID: 24727326
Update of IGF-1 receptor inhibitor (ganitumab, dalotuzumab, cixutumumab, teprotumumab and figitumumab) effects on cancer therapy, PMID: 28427155
A Phase I Trial of the IGF-1R Antibody Ganitumab (AMG 479) in Combination with Everolimus (RAD001) and Panitumumab in Patients with Advanced Cancer, PMID: 29572245
Ganitumab with either exemestane or fulvestrant for postmenopausal women with advanced, hormone-receptor-positive breast cancer: a randomised, controlled, double-blind, phase 2 trial, PMID: 23414585
IGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice, PMID: 24492468
Update of IGF-1 receptor inhibitor (ganitumab, dalotuzumab, cixutumumab, teprotumumab and figitumumab) effects on cancer therapy, PMID: 28427155
A Phase I Trial of the IGF-1R Antibody Ganitumab (AMG 479) in Combination with Everolimus (RAD001) and Panitumumab in Patients with Advanced Cancer, PMID: 29572245
Ganitumab with either exemestane or fulvestrant for postmenopausal women with advanced, hormone-receptor-positive breast cancer: a randomised, controlled, double-blind, phase 2 trial, PMID: 23414585
IGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice, PMID: 24492468
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
insulin-like growth factor 1 receptor
NCBI Official Synonym Full Names
insulin-like growth factor 1 receptor
NCBI Official Symbol
IGF1R
NCBI Official Synonym Symbols
IGFR; CD221; IGFIR; JTK13
NCBI Protein Information
insulin-like growth factor 1 receptor; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor
UniProt Protein Name
Insulin-like growth factor 1 receptor
UniProt Gene Name
IGF1R
UniProt Synonym Gene Names
IGF-I receptor
UniProt Entry Name
IGF1R_HUMAN
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Product Notes
The IGF1R igf1r (Catalog #AAA120018) is an Antibody produced from Homo sapiens and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Ganitumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Ganitumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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