WB (Western Blot)
(Western blot analysis of lysate from Hela cell line, using GPR56. AAA283470 was diluted at 1:2000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Mouse anti-Human GPR56 Monoclonal Antibody | anti-GPR56 antibody
GPR56
Gene Names
ADGRG1; BFPP; BPPR; GPR56; TM7LN4; TM7XN1
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified Mouse Monoclonal Antibody (Mab)
Synonyms
GPR56, Antibody; GPR56; G-protein coupled receptor 56; Protein TM7XN1; GPR56 N-terminal fragment; GPR56 NT; GPR56(N); GPR56 extracellular subunit; GPR56 subunit alpha; GPR56 C-terminal fragment; GPR56 CT; GPR56(C); GPR56 seven-transmembrane subunit; GPR56 7TM; GPR56 subunit beta; TM7LN4; TM7XN1; anti-GPR56 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1443CT377.65.29
Specificity
This antibody is generated from a mouse immunized with a recombinant protein.
Purity/Purification
Purified Mouse Monoclonal Antibody (Mab)
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Sequence Length
687
Applicable Applications for anti-GPR56 antibody
ELISA, WB (Western Blot)
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of lysate from Hela cell line, using GPR56. AAA283470 was diluted at 1:2000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
WB (Western Blot)
(Western blot analysis of lysate from Hela cell line, using GPR56. AAA283470 was diluted at 1:2000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
WB (Western Blot)
(All lanes : Anti-GPR56 Antibody at 1:1000 dilutionLane 1: Hela whole cell lysatesLane 2: U87-MG whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 78 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(All lanes : Anti-GPR56 Antibody at 1:1000 dilutionLane 1: Hela whole cell lysatesLane 2: U87-MG whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 78 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(All lanes : Anti-GPR56 Antibody at 1:1000 dilutionLane 1: Hela whole cell lysatesLane 2: U87-MG whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 78 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(All lanes : Anti-GPR56 Antibody at 1:1000 dilutionLane 1: Hela whole cell lysatesLane 2: U87-MG whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 78 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-GPR56 antibody
Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling, specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and, during melanoma progression, regulates VEGFA production and angiogenesis through PRKCA; unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis.
Product Categories/Family for anti-GPR56 antibody
References
Liu M.,et al.Genomics 55:296-305(1999).
Zendman A.J.W.,et al.FEBS Lett. 446:292-298(1999).
Kaighin V.A.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zendman A.J.W.,et al.FEBS Lett. 446:292-298(1999).
Kaighin V.A.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
77738
NCBI Official Full Name
G-protein coupled receptor 56 isoform b
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor G1
NCBI Official Symbol
ADGRG1
NCBI Official Synonym Symbols
BFPP; BPPR; GPR56; TM7LN4; TM7XN1
NCBI Protein Information
G-protein coupled receptor 56
UniProt Protein Name
G-protein coupled receptor 56
UniProt Gene Name
GPR56
UniProt Synonym Gene Names
TM7LN4; TM7XN1; GPR56 NT; GPR56(N); GPR56 CT; GPR56(C); GPR56 7TM
UniProt Entry Name
GPR56_HUMAN
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Product Notes
The GPR56 gpr56 (Catalog #AAA283470) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GPR56 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPR56 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the GPR56 gpr56 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR56, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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