SDS-PAGE
(SDS-PAGE Analysis Purified GNAQ Mouse Monoclonal Antibody (GNAQ/2434). Confirmation of Integrity and Purity of the Antibody.)
Mouse anti-Human Guanine nucleotide-binding protein alpha-q/GNAQ/G-ALPHA-q Monoclonal Antibody | anti-GNAQ antibody
Guanine nucleotide-binding protein alpha-q/GNAQ/G-ALPHA-q
Gene Names
GNAQ; GAQ; SWS; CMC1; G-ALPHA-q
Reactivity
Human
Applications
Immunofluorescence, Flow Cytometry, Functional Assay, ELISA
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
Guanine nucleotide-binding protein alpha-q/GNAQ/G-ALPHA-q, Antibody; Guanine nucleotide-binding protein alpha-q/GNAQ/G-ALPHA-q; CMC1; G alpha Q; G protein alpha Q; GAQ; guanine nucleotide binding protein (G protein); q polypeptide; Guanine nucleotide-binding protein G(q) subunit alpha; SWS; anti-GNAQ antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b, kappa
Clone Number
GNAQ/2434
Specificity
GNAQis 359 amino acids long and is identical in all but 1 amino acid residue to the Mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA sequence included several small deletions and insertions that altered the reading frame, multiple single based changes, and a premature termination codon in the open reading frame, all hallmarks of a processed pseudogene. Probes derived from human GNAQ cDNA sequence mapped both chromosomes 2 and 9 in higher constringency genomic blot analyses of DNA from a panel of human/rodent hybrid cell lines.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
359
Applicable Applications for anti-GNAQ antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry), ELISA
Positive Control
HL-60, MOLT-4 and MCF-7 cells. Predominantly expressed in ovary, prostate, testis and colon.
Immunogen
Recombinant full-length human GNAQ protein
Cellular Localization
Cytoplasmic and Cell Surface
Hu-chromosome Location
9q21.2
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C.
Non-hazardous. No MSDS required.
Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified GNAQ Mouse Monoclonal Antibody (GNAQ/2434). Confirmation of Integrity and Purity of the Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified GNAQ Mouse Monoclonal Antibody (GNAQ/2434). Confirmation of Integrity and Purity of the Antibody.)
References
1. Strathmann, M. and Simon, M.I. 1990. Proc. Natl. Acad. Sci. USA 87: 9113-9117. 2. Simon, M.I., et al. 1991. Diversity of G proteins in signal transduction. Science 252: 802-808. 3. Chen, B., et al. 1996. Biochim. Biophys. Acta 1281:125-12
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45kDa
NCBI Official Full Name
guanine nucleotide-binding protein G(q) subunit alpha
NCBI Official Synonym Full Names
G protein subunit alpha q
NCBI Official Symbol
GNAQ
NCBI Official Synonym Symbols
GAQ; SWS; CMC1; G-ALPHA-q
NCBI Protein Information
guanine nucleotide-binding protein G(q) subunit alpha
UniProt Protein Name
Guanine nucleotide-binding protein G(q) subunit alpha
UniProt Gene Name
GNAQ
UniProt Synonym Gene Names
GAQ
UniProt Entry Name
GNAQ_HUMAN
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Product Notes
The GNAQ gnaq (Catalog #AAA214994) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Guanine nucleotide-binding protein alpha-q/GNAQ/G-ALPHA-q reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Guanine nucleotide-binding protein alpha-q/GNAQ/G-ALPHA-q can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry), ELISA. Researchers should empirically determine the suitability of the GNAQ gnaq for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Guanine nucleotide-binding protein alpha-q/GNAQ/G-ALPHA-q, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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