IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human colon, using HIF-1 beta Antibody .)
HIF-1 beta Recombinant Antibody | HIF-1beta recombinant antibody
HIF-1 beta Rabbit mAb
Gene Names
ARNT; HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Affinity-chromatography
Synonyms
HIF-1 beta, Recombinant Antibody; HIF-1 beta Rabbit mAb; ARNT;HIF-1beta;HIF1B;HIF1BETA;TANGO;bHLHe2; HIF-1beta recombinant antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Specificity
HIF-1 beta Antibody detects endogenous levels of total HIF-1 beta
Purity/Purification
Affinity-chromatography
Form/Format
Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applicable Applications for HIF-1beta recombinant antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human HIF-1 beta
Preparation and Storage
Store at +4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human colon, using HIF-1 beta Antibody .)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human colon, using HIF-1 beta Antibody .)
WB (Western Blot)
(Western blot analysis of HIF-1 beta expression in Human fetal kidney lysate.)
WB (Western Blot)
(Western blot analysis of HIF-1 beta expression in Human fetal kidney lysate.)
Related Product Information for HIF-1beta recombinant antibody
HIF-1beta is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1beta plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1beta expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1beta plays an important role in pancreatic beta-cell function.
Product Categories/Family for HIF-1beta recombinant antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
86,636 Da
NCBI Official Full Name
aryl hydrocarbon receptor nuclear translocator isoform 4
NCBI Official Synonym Full Names
aryl hydrocarbon receptor nuclear translocator
NCBI Official Symbol
ARNT
NCBI Official Synonym Symbols
HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta
NCBI Protein Information
aryl hydrocarbon receptor nuclear translocator; dioxin receptor, nuclear translocator; class E basic helix-loop-helix protein 2; hypoxia-inducible factor 1, beta subunit
UniProt Protein Name
Aryl hydrocarbon receptor nuclear translocator
UniProt Gene Name
ARNT
UniProt Synonym Gene Names
BHLHE2; ARNT protein; bHLHe2; HIF-1-beta; HIF1-beta
UniProt Entry Name
ARNT_HUMAN
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Product Notes
The HIF-1beta arnt (Catalog #AAA315229) is a Recombinant Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HIF-1 beta Rabbit mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HIF-1 beta can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the HIF-1beta arnt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HIF-1 beta, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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