IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human gastric cancer tissue, untreated (left) or lambda phosphatase-treated (right), using Recombinant Phospho-Histone H2A-X (Ser139) Antibody, Rabbit Monoclonal (#AAA259160) at 1:200 dilution.)
Histone H2A.X Recombinant Antibody | H2A.X recombinant antibody
Phospho-Histone H2A.X (Ser139) Antibody, Rabbit Mab
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Protein A
Synonyms
Histone H2A.X, Recombinant Antibody; Phospho-Histone H2A.X (Ser139) Antibody, Rabbit Mab; H2A histone family member X; Anti-H2A.X Antibody; Anti-H2A/X Antibody; Anti-H2AX Antibody; H2A.X recombinant antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
#0016
Specificity
Human Phospho-Histone H2A.X (Ser139). Human Phospho-Histone H2A.X Ser140 of P16104 in UniProt historically has been referenced as Ser139.
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for H2A.X recombinant antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to residues around Ser139 of Human Phospho-Histone H2A.X
Preparation
This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to residues around Ser139 of Human Phospho-Histone H2A.X.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human gastric cancer tissue, untreated (left) or lambda phosphatase-treated (right), using Recombinant Phospho-Histone H2A-X (Ser139) Antibody, Rabbit Monoclonal (#AAA259160) at 1:200 dilution.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human gastric cancer tissue, untreated (left) or lambda phosphatase-treated (right), using Recombinant Phospho-Histone H2A-X (Ser139) Antibody, Rabbit Monoclonal (#AAA259160) at 1:200 dilution.)
WB (Western Blot)
(Western blot analysis of extracts from serum-starved NIH-3T3, untreated (-); treated with UV (30 min; +), using Phospho-Histone H2A.X (Ser139) rabbit monoclonal Antibody (#AAA259160) at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts from serum-starved NIH-3T3, untreated (-); treated with UV (30 min; +), using Phospho-Histone H2A.X (Ser139) rabbit monoclonal Antibody (#AAA259160) at 1:1000 dilution.)
Related Product Information for H2A.X recombinant antibody
H2AFX variants are associated with an increased risk of breast cancer (BC). H2AFX gene encodes a member of the H2A histone family which is central in the detection of and response to DNA double-strand breaks. In somatic cells, H2afx and Mdc1 are close functional partners in DNA repair and damage response. Due to the critical role of the H2AX histone variant in double-strand break repair, genetic variants in the H2AX gene, H2AFX, may influence cancer susceptibility. H2AFX encodes a histone variant involved in signaling sites of DNA damage and recruiting repair factors. Genetic variants in H2AFX may influence the risk of non-Hodgkin lymphoma (NHL), a heterogeneous group of lymphoid tumors that are characterized by chromosomal translocations.
Similar Products
Product Notes
The H2A.X (Catalog #AAA259160) is a Recombinant Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-Histone H2A.X (Ser139) Antibody, Rabbit Mab reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Histone H2A.X can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the H2A.X for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Histone H2A.X, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.