Rabbit anti-Human HLA-DP Monoclonal Antibody | anti-HLA-DP antibody

HLA-DP (MHC II)

Cat. Num. AAA214757

• Gene Names: HLA-DPB1; DPB1; HLA-DP; HLA-DPB; HLA-DP1B
• Reactivity: Human
• Applications: Immunofluorescence, Flow Cytometry, Functional Assay, ELISA
• Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: HLA-DP, Antibody; HLA-DP (MHC II); HLA class II histocompatibility antigen DP alpha 1 chain; HLA DP1A; HLA SB alpha chain; HLADP; HLADPA1; HLASB; HLASB histocompatibility type; Human MHC class II HLA SB alpha; Major histocompatibility complex class II DP alpha 1; MHC class II DP3 alpha; MHC class II DPA1; PLT1; Primed lymphocyte test 1; anti-HLA-DP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG
• Clone Number: HLA-DPB1/2862R
• Specificity: Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35kDa) and beta (27-30kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 258

• Applicable Applications for anti-HLA-DP antibody: IF (Immunofluorescence), FCM/FACS (Flow Cytometry), ELISA
• Immunogen: Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
• Positive Control: Raji Cells. Tonsil or Lymph Node
• Cellular Localization: Cell Surface
• Chromosome Location: 6p21.3
• Positive Control: Raji cells. Tonsil or lymph node.
• Preparation and Storage: Antibody with azide - store at 2 to 8 degree C.; Antibody without azide - store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IF (Immunofluorescence)

(Immunofluorescence Analysis of Human Raji cells labeling HLA-DP with HLA-DP Rabbit Recombinant Monoclonal (HLA-DPB1/2862R) followed by Goat anti-rabbit IgG-CF488 (Green). The nuclear counterstain is Reddot (Red).)

FCM/FACS (Flow Cytometry)

(Flow Cytometric Analysis of Raji cells HLA-DP Rabbit Recombinant Monoclonal Antibody (HLA-DPB1/2862R) followed by goat anti-Rabbit IgG-CF488 (Blue); Isotype Control (Red).)

SDS-PAGE

(SDS-PAGE Analysis Purified HLA-DP Rabbit Recombinant Monoclonal Ab (HLA-DPB1/2862R). Confirmation of Purity and Integrity of Antibody.)

Related Product Information for anti-HLA-DP antibody

Recombinant Rabbit Monoclonal Antibody

References

Babusikova O., et al. Neoplasma, 1985, 32(6):657-62.; Polakova K., et al. Neoplasma, 1985, 32(6):641-8.

NCBI and Uniprot Product Information

• NCBI GI #: 24797076
• NCBI GeneID: 3115
• NCBI Accession #: NP_002112.3
• NCBI GenBank Nucleotide #: NM_002121.5
• UniProt Accession #: P04440; A0PFJ7; A5I886; A8YPB3; B5U8B4; B7VF80; B7VF87; B8ZX68; B8ZYT0; B9W5S8; B9W6F7; B9W6F9
• Molecular Weight: 33-35kDa
• NCBI Official Full Name: HLA class II histocompatibility antigen, DP beta 1 chain
• NCBI Official Synonym Full Names: major histocompatibility complex, class II, DP beta 1
• NCBI Official Symbol: HLA-DPB1
• NCBI Official Synonym Symbols: DPB1; HLA-DP; HLA-DPB; HLA-DP1B
• NCBI Protein Information: HLA class II histocompatibility antigen, DP beta 1 chain
• UniProt Protein Name: HLA class II histocompatibility antigen, DP beta 1 chain
• UniProt Gene Name: HLA-DPB1
• UniProt Synonym Gene Names: HLA-DP1B