Mouse HLA-DR Monoclonal Antibody | anti-HLA-DR antibody
Anti-HLA-DR Purified Low Endotoxin
Gene Names
HLA-DQB1; IDDM1; CELIAC1; HLA-DQB
Reactivity
Dog, Non-human primates, Human
Applications
Functional Assay, Immunocytochemistry, Immunohistochemistry, Western Blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
HLA-DR, Antibody; Anti-HLA-DR Purified Low Endotoxin; anti-HLA-DR antibody
Host
Mouse
Reactivity
Dog, Non-human primates, Human
Clonality
Monoclonal
Isotype
IgG2a kappa
Clone Number
L243
Specificity
The mouse monoclonal antibody L243 recognizes specifically an extracellular epitope on HLA-DR molecules, both peptide-loaded and empty.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 um filter sterilized. Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.
Concentration
1 mg/ml (varies by lot)
Sequence Length
42
Applicable Applications for anti-HLA-DR antibody
FA (Functional Assay), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry)
Immunogen
Human B lymphocytes
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-HLA-DR antibody
HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
HLA-DR, partial
NCBI Official Synonym Full Names
major histocompatibility complex, class II, DQ beta 1
NCBI Official Symbol
HLA-DQB1
NCBI Official Synonym Symbols
IDDM1; CELIAC1; HLA-DQB
NCBI Protein Information
HLA class II histocompatibility antigen, DQ beta 1 chain
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Product Notes
The HLA-DR (Catalog #AAA128657) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-HLA-DR Purified Low Endotoxin reacts with Dog, Non-human primates, Human and may cross-react with other species as described in the data sheet. AAA Biotech's HLA-DR can be used in a range of immunoassay formats including, but not limited to, FA (Functional Assay), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the HLA-DR for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HLA-DR, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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