IHC (Immunohiostchemistry)
(Immunohistochemistry of hnRNP K in paraffin-embedded Human lung cancer tissue using hnRNP K Rabbit mAb at dilution 1/50)
hnRNP K Monoclonal Antibody | anti-hnRNPK antibody
hnRNP K Rabbit mAb
Gene Names
HNRNPK; CSBP; TUNP; HNRPK
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
hnRNP K, Antibody; hnRNP K Rabbit mAb; AUKS; CSBP; TUNP; HNRPK; anti-hnRNPK antibody
Host
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
S07-5H0
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration
0.3mg/ml (varies by lot)
Applicable Applications for anti-hnRNPK antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human hnRNP K
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of hnRNP K in paraffin-embedded Human lung cancer tissue using hnRNP K Rabbit mAb at dilution 1/50)
IHC (Immunohiostchemistry)
(Immunohistochemistry of hnRNP K in paraffin-embedded Human lung cancer tissue using hnRNP K Rabbit mAb at dilution 1/50)
WB (Western Blot)
(Western blot detection of hnRNP K in K562,PC3,Hela cell lysates using hnRNP K Rabbit mAb(1:500 diluted).Predicted band size:51kDa.Observed band size:62kDa.)
WB (Western Blot)
(Western blot detection of hnRNP K in K562,PC3,Hela cell lysates using hnRNP K Rabbit mAb(1:500 diluted).Predicted band size:51kDa.Observed band size:62kDa.)
Related Product Information for anti-hnRNPK antibody
One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction . As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
Product Categories/Family for anti-hnRNPK antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,976 Da
NCBI Official Full Name
heterogeneous nuclear ribonucleoprotein K isoform a
NCBI Official Synonym Full Names
heterogeneous nuclear ribonucleoprotein K
NCBI Official Symbol
HNRNPK
NCBI Official Synonym Symbols
CSBP; TUNP; HNRPK
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein K; dC-stretch binding protein; transformation upregulated nuclear protein
UniProt Protein Name
Heterogeneous nuclear ribonucleoprotein K
UniProt Gene Name
HNRNPK
UniProt Synonym Gene Names
HNRPK; hnRNP K; TUNP
UniProt Entry Name
HNRPK_HUMAN
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Product Notes
The hnRNPK hnrnpk (Catalog #AAA314378) is an Antibody produced from Recombinant Rabbit and is intended for research purposes only. The product is available for immediate purchase. The hnRNP K Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's hnRNP K can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the hnRNPK hnrnpk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "hnRNP K, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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