Mouse HP-1gamma Monoclonal Antibody | anti-HP-1gamma antibody

HP-1gamma Mouse Monoclonal Antibody (3B9)

Cat. Num. AAA320524

• Gene Names: CBX3; HECH; HP1-GAMMA; HP1Hs-gamma
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: HP-1gamma, Antibody; HP-1gamma Mouse Monoclonal Antibody (3B9); Chromobox protein homolog 3 (HECH)(Heterochromatin protein 1 homolog gamma)(HP1 gamma)(Modifier 2 protein); anti-HP-1gamma antibody

• Host: Mouse
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Clone Number: 3B9
• Specificity: The antibody detects endogenous HP-1gamma protein
• Purity/Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-HP-1gamma antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Recombinant Protein of HP-1gamma
• Modification: Unmodified/Total
• Preparation and Storage: Store at -20 degree C/1 year

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded Human Placenta Tissue using HP-1? Mouse mAb diluted at 1:200)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using HP-1? Mouse mAb diluted at 1:200)

WB (Western Blot)

(Western blot analysis of 1) Hela Cell Lysate. 2)3T3 Cell Lysate. 3) PC12 Cell Lysate using HP-1? Mouse mAb diluted at 1:1000.)

Related Product Information for anti-HP-1gamma antibody

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane.The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites ofultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]

Product Categories/Family for anti-HP-1gamma antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 15082258
• NCBI GeneID: 11335
• NCBI Accession #: NP_009207.2
• NCBI GenBank Nucleotide #: NM_007276.4
• UniProt Accession #: Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6
• Molecular Weight: 20,811 Da
• NCBI Official Full Name: chromobox protein homolog 3
• NCBI Official Synonym Full Names: chromobox homolog 3
• NCBI Official Symbol: CBX3
• NCBI Official Synonym Symbols: HECH; HP1-GAMMA; HP1Hs-gamma
• NCBI Protein Information: chromobox protein homolog 3; HP1 gamma homolog; modifier 2 protein; heterochromatin-like protein 1; heterochromatin protein HP1 gamma; heterochromatin protein 1 homolog gamma; chromobox homolog 3 (HP1 gamma homolog, Drosophila)
• UniProt Protein Name: Chromobox protein homolog 3
• UniProt Gene Name: CBX3
• UniProt Synonym Gene Names: HP1 gamma
• UniProt Entry Name: CBX3_HUMAN