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product-image-AAA305253_IHC13.jpg IHC (Immunohiostchemistry) (The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31083 (HP Antibody) at dilution 1/25, on the right is treated with the fusion protein.)

Rabbit anti-Human HP Polyclonal Antibody | anti-HP antibody

HP Antibody

Gene Names
HP; BP; HPA1S; HP2ALPHA2
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Synonyms
HP, Antibody; HP Antibody; haptoglobin, BP, HPA1S, HP2ALPHA2; anti-HP antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total HP protein.
Form/Format
Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Sequence Length
1365
Applicable Applications for anti-HP antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to a region derived from 162-406 amino acids of human haptoglobin
Target Name
HP
Preparation and Storage
Store at -20 degree C/1 year

IHC (Immunohiostchemistry)

(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31083 (HP Antibody) at dilution 1/25, on the right is treated with the fusion protein.)

product-image-AAA305253_IHC13.jpg IHC (Immunohiostchemistry) (The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31083 (HP Antibody) at dilution 1/25, on the right is treated with the fusion protein.)

Application Data

(Gel: 10%SDS-PAGE Lysate: 30 ug Human brain gliomas tissue lysate Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 seconds)

product-image-AAA305253_AD15.jpg Application Data (Gel: 10%SDS-PAGE Lysate: 30 ug Human brain gliomas tissue lysate Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 seconds)
Related Product Information for anti-HP antibody
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-HP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
38,452 Da
NCBI Official Full Name
Homo sapiens haptoglobin, mRNA
NCBI Official Synonym Full Names
haptoglobin
NCBI Official Symbol
HP
NCBI Official Synonym Symbols
BP; HPA1S; HP2ALPHA2
NCBI Protein Information
haptoglobin
UniProt Protein Name
Haptoglobin
UniProt Gene Name
HP
UniProt Entry Name
HPT_HUMAN

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Product Notes

The HP hp (Catalog #AAA305253) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HP can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the HP hp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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