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product-image-AAA312240_IHC10.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.)

Rabbit HTRA2/Omi Monoclonal Antibody | anti-HTRA2/Omi antibody

HTRA2/Omi Antibody

Gene Names
HTRA2; OMI; PARK13; PRSS25
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Immunohistochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
HTRA2/Omi, Antibody; HTRA2/Omi Antibody; High temperature requirement protein A2 antibody; HTRA 2 antibody; HtrA like serine protease antibody; HtrA serine peptidase 2 antibody; HtrA; E. coli; homolog of; 2 antibody; HtrA2 antibody; HTRA2_HUMAN antibody; mitochondrial antibody; Omi stress regulated endoprotease antibody; Omi stress-regulated endoprotease antibody; PARK 13 antibody; PARK13 antibody; Protease serine 25 antibody; PRSS 25 antibody; PRSS25 antibody; Serine protease 25 antibody; Serine protease HTRA2 antibody; Serine protease HTRA2 mitochondrial antibody; Serine protease htra2 mitochondrial precursor antibody; Serine protease omi antibody; Serine proteinase OMI antibody; anti-HTRA2/Omi antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
ST54-05
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-HTRA2/Omi antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.)

product-image-AAA312240_IHC10.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.)

product-image-AAA312240_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.)

product-image-AAA312240_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.)

WB (Western Blot)

(Western blot analysis of HtrA2 on 293 cell lysates using anti-HtrA2 antibody at 1/1, 000 dilution.)

product-image-AAA312240_WB15.jpg WB (Western Blot) (Western blot analysis of HtrA2 on 293 cell lysates using anti-HtrA2 antibody at 1/1, 000 dilution.)
Related Product Information for anti-HTRA2/Omi antibody
The human homolog of the E. Coli htrA gene product, HtrA, is identified in osteoarthritic cartilage and is repressed in SV40-transformed fibroblast. The gene encoding HtrA protein is highly conserved among mammalian species and belongs to the serine protease family. The HtrA protein contains an IGF-binding domain and exhibits endoproteolytic activity, including autocatalytic cleavage. HtrA is a secreted protein that is expressed in heterologous systems. HtrA plays a role in the degradation of denatured proteins and cell growth regulation. Human HtrA2 (also designated Omi), a novel member of the HtrA serine protease family, is highly homologous to HtrA (also known as L56 and HtrA1). HtrA2 is a ubiquitously expressed nuclear protease that is capable of autoproteolysis. The HtrA2 protein exists as two polypeptides and as an alternatively spliced form called D-Omi, which is predominately expressed in the kidney, colon and thyroid. Due to a modified PDZ domain, D-Omi does not interact with the known partner of HtrA2, the Mxi2 protein. Like HtrA, HtrA2 is involved in the degradation aberrantly folded proteins during conditions of cellular stress, suggesting that it may possess a chaperone-like role under normal conditions.
Product Categories/Family for anti-HTRA2/Omi antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,841 Da
NCBI Official Full Name
serine protease HTRA2, mitochondrial isoform 1 preproprotein
NCBI Official Synonym Full Names
HtrA serine peptidase 2
NCBI Official Symbol
HTRA2
NCBI Official Synonym Symbols
OMI; PARK13; PRSS25
NCBI Protein Information
serine protease HTRA2, mitochondrial; serine protease 25; protease, serine, 25; serine proteinase OMI; HtrA-like serine protease; Omi stress-regulated endoprotease; high temperature requirement protein A2
UniProt Protein Name
Serine protease HTRA2, mitochondrial
UniProt Gene Name
HTRA2
UniProt Synonym Gene Names
OMI; PRSS25; HtrA2
UniProt Entry Name
HTRA2_HUMAN

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Product Notes

The HTRA2/Omi htra2 (Catalog #AAA312240) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HTRA2/Omi Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HTRA2/Omi can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the HTRA2/Omi htra2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HTRA2/Omi, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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